Evidence map›Paper›PMID 26475844›Full record

Trial reportPeritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

Effects of Ginger on Serum Lipids and Lipoproteins in Peritoneal Dialysis Patients: A Randomized Controlled Trial.

Hadi Tabibi, Hossein Imani, Shahnaz Atabak, Iraj Najafi, Mehdi Hedayati, Leila Rahmani

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Effect ofEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Effects of GingerEvidence-based complementary and alternative medicine : eCAM · 2018
    Review
  11. Review
  12. Chitosan/Alginate-LoadedReproductive medicine and biology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Hadi TabibiDepartment of Clinical Nutrition & Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran hadtabibi@yahoo.com.
Hossein ImaniFaculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Shahnaz AtabakDepartment of Nephrology, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Iraj NajafiDepartment of Nephrology, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Mehdi HedayatiCellular and Molecular Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Leila RahmaniShafa Clinic, Tehran, Islamic Republic of Iran.
Shahid Beheshti University of Medical Sciences · IRNational Nutrition and Food Technology Research Institute · IRResearch Institute for Endocrine Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelled♦

backgroundIn peritoneal dialysis (PD) patients, one of the major risk factors for cardiovascular disease is lipid abnormalities. This study was designed to investigate the effects of ginger supplementation on serum lipids and lipoproteins in PD patients. ♦

methodsIn this randomized, double-blind, placebo-controlled trial, 36 PD patients were randomly assigned to either the ginger or the placebo group. The patients in the ginger group received 1,000 mg ginger daily for 10 weeks, while the placebo group received corresponding placebos. At baseline and at the end of week 10, 7 mL of blood were obtained from each patient after a 12- to 14-hour fast, and serum concentrations of triglyceride, total cholesterol, low density lipoprotein-cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C), and lipoprotein (a) [Lp (a)] were measured. ♦

resultsSerum triglyceride concentration decreased significantly up to 15% in the ginger group at the end of week 10 compared with baseline (p < 0.01), and the reduction was significant in comparison with the placebo group (p < 0.05). There were no significant differences between the 2 groups in mean changes of serum total cholesterol, LDL-C, HDL-C, and Lp (a). ♦

conclusionThis study indicates that daily administration of 1,000 mg ginger reduces serum triglyceride concentration, which is a risk factor for cardiovascular disease, in PD patients.

Indexed as

Dietary SupplementsPeritoneal DialysisAdultAgedDouble-Blind MethodFemaleHumansHyperlipidemiasIranKidney Failure, ChronicLipidsLipoproteinsMaleMiddle AgedRegistriesZingiber officinaleLipidsLipoproteinscardiovascular diseaseGingerlipidslipoproteinsperitoneal dialysis

Identifiers

PMID26475844
PMCPMC4803358
OpenAlexW2258205495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.