ArticleQJM : monthly journal of the Association of Physicians2016
Outcome of Guillain-Barre syndrome patients with respiratory paralysis.
Article in QJM : monthly journal of the Association of Physicians, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guidelines for Neuroprognostication in Adults with Guillain-Barré Syndrome.Neurocritical care · 2023Guideline
- Sinomenine ameliorates experimental autoimmune neuritis by suppressing pro-inflammatory immune components and restoring immune balance.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Efgartigimod as a potential alternative to intravenous immunoglobulin in Guillain-Barré syndrome: a retrospective study.Frontiers in immunology · 2026Article
- Association Between Hematoma Edema Complex and Outcomes of Primary Intracerebral Hemorrhage.Neurocritical care · 2025Article
- Outcome of Cerebral Venous Thrombosis Requiring Mechanical Ventilation.Journal of clinical medicine · 2025Article
- A superior tool for predicting sepsis in SAH patients: The nomogram outperforms SOFA score.PloS one · 2025Article
- Article
- Temporal Pattern of Individual Neurological Function Recovery in Guillain-Barré Syndrome.Journal of clinical medicine · 2024Article
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- Article
- Manual therapeutic plasma exchange for treatment of a dog with suspected acute canine polyradiculoneuritis.Acta veterinaria Scandinavica · 2023Article
- Article
- Identification of factors affecting outcomes in patients with Guillain Barre syndrome.Medicine and pharmacy reports · 2022Article
- Risk Factors for Mechanical Ventilation in Patients with Guillain-Barré Syndrome.Neurocritical care · 2022Article
- Guillain-Barré syndrome in low-income and middle-income countries: challenges and prospects.Nature reviews. Neurology · 2021Review
- Intensive Care and Treatment of Severe Guillain-Barré Syndrome.Frontiers in pharmacology · 2021Review
- Inclusion of Mechanical Ventilation in Severity Staging of Tuberculous Meningitis Improves Outcome Prediction.The American journal of tropical medicine and hygiene · 2020Article
- A Predictive Model for Respiratory Failure and Determining the Risk Factors of Prolonged Mechanical Ventilation in Children with Guillain-Barre Syndrome.Iranian journal of child neurology · 2020Article
- Integrated Chinese and Western Medicine for Acute Guillain-barré Syndrome Treatment.Translational neuroscience · 2020Article
- Influenza Vaccination and Guillain-Barré Syndrome: Reality or Fear.Journal of translational internal medicine · 2019Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsTo evaluate the outcome of patients with Guillain -: Barre syndrome (GBS) having respiratory failure treated with modified intubation policy. DESIGN AND
methodsConsecutive patients with GBS having single breath count below 12 and respiratory rate >30/min were included and their clinical details noted. The patients were intubated and mechanically ventilated (MV) if their PaO2 was <60 mmHg on venturi mask, PaCo2 > 50 mmHg or pH < 7.3. Their electrophysiological subtypes and complications were noted. The hospital mortality and 3 months outcome were compared in MV and those could be managed without MV even with respiratory compromise.
resultsOut of 369 patients, 102 (27.6%) patients had respiratory compromise who were included in this study. Of the patients with respiratory compromise, 44 (43.1%) were intubated and mechanically ventilated after a median of 4 days of hospitalization. The median duration of MV was 21 (range 1-88) days. The patients with autonomic dysfunction (56.8% vs. 19%), facial weakness (78% vs. 36.2%), bulbar weakness (81.8% vs. 31%), severe weakness (63.8% vs. 31%) and high transaminase level (47.7% vs. 25.9%) needed MV more frequently. In our study, 6.8% patients died and 26.6% had poor outcome which was similar between MV and non-MV patients. The MV patients had longer hospitalization and more complications compared with non-MV group.
conclusionIn GBS patients with respiratory compromise, conservative intubation does not increase mortality and disability.
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