Evidence map›Paper›PMID 26474508›Full record

Observational studyJournal of vascular surgery2016

The effect of social integration on outcomes after major lower extremity amputation.

Alexander T Hawkins, Anthony J Pallangyo, Ayesiga M Herman, Maria J Schaumeier, Ann D Smith, Nathanael D Hevelone, David M Crandell, Louis L Nguyen

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of vascular surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Technology for monitoring everyday prosthesis use: a systematic review.Journal of neuroengineering and rehabilitation · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander T HawkinsCenter for Surgery and Public Health, Boston, Mass; Department of Vascular and Endovascular Surgery, Brigham & Women's Hospital, Boston, Mass; Department of Surgery, Massachusetts General Hospital, Boston, Mass.
Anthony J PallangyoDepartment of Surgery, Kilimanjaro Christian Medical Center, Moshi, Tanzania.
Ayesiga M HermanDepartment of Surgery, Kilimanjaro Christian Medical Center, Moshi, Tanzania.
Maria J SchaumeierCenter for Surgery and Public Health, Boston, Mass.
Ann D SmithCenter for Surgery and Public Health, Boston, Mass; Department of Vascular and Endovascular Surgery, Brigham & Women's Hospital, Boston, Mass.
Nathanael D HeveloneCenter for Surgery and Public Health, Boston, Mass; Department of Vascular and Endovascular Surgery, Brigham & Women's Hospital, Boston, Mass.
David M CrandellDepartment of Surgery, Massachusetts General Hospital, Boston, Mass; Spaulding Rehabilitation Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Louis L NguyenCenter for Surgery and Public Health, Boston, Mass; Department of Vascular and Endovascular Surgery, Brigham & Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass. Electronic address: llnguyen@partners.org.

Funding

HARVARD-LONGWOOD RESEARCH TRAINING IN VASCULAR SURGERYT32HL007734 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI FERRAN, CHRISTIANE, LOGERFO, FRANK W · 1993 to 2023
$10.5M
NHLBI NIH HHS HL007734NHLBI NIH HHS T32 HL007734
6 · The paper itself

Abstract

objectiveMajor lower extremity (MLE) amputation is a common procedure that results in a profound change in a patient's life. We sought to determine the association between social support and outcomes after amputation. We hypothesized that patients with greater social support will have better post amputation outcomes.

methodsFrom November 2011 to May 2013, we conducted a cross-sectional, observational, multicenter study. Social integration was measured by the social integration subset of the Short Form Craig Handicap Assessment and Reporting Technique. Systemic social support was assessed by comparing a United States and Tanzanian population. Walking function was measured using the 6-minute walk test and quality of life (QoL) was measured using the EuroQol-5D.

resultsWe recruited 102 MLE amputees. Sixty-three patients were enrolled in the United States with a mean age of 58.0. Forty-two (67%) were male. Patients with low social integration were more likely to be unable to ambulate (no walk 39% vs slow walk 23% vs fast walk 10%; P = .01) and those with high social integration were more likely to be fast walkers (no walk 10% vs slow walk 59% vs fast walk 74%; P = .01). This relationship persisted in a multivariable analysis. Increasing social integration scores were also positively associated with increasing QoL scores in a multivariable analysis (β, .002; standard error, 0.0008; P = .02). In comparing the United States population with the Tanzanian cohort (39 subjects), there were no differences between functional or QoL outcomes in the systemic social support analysis.

conclusionsIn the United States population, increased social integration is associated with both improved function and QoL outcomes among MLE amputees. Systemic social support, as measured by comparing the United States population with a Tanzanian population, was not associated with improved function or QoL outcomes. In the United States, steps should be taken to identify and aid amputees with poor social integration.

Indexed as

Social BehaviorSocial SupportAdultAgedAged, 80 and overAmputation, SurgicalAmputeesBostonChi-Square DistributionCross-Sectional StudiesExercise TestFemaleHumansLinear ModelsLower ExtremityMale

Identifiers

PMID26474508
PMCPMC4739523

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.