ArticlePLoS computational biology2015
Electrosensory Midbrain Neurons Display Feature Invariant Responses to Natural Communication Stimuli.
Article in PLoS computational biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Burst firing optimizes invariant coding of natural communication signals by electrosensory neural populations.iScience · 2025Article
- Supervised learning algorithm for analysis of communication signals in the weakly electric fish Apteronotus leptorhynchus.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024Article
- Descending pathways increase sensory neural response heterogeneity to facilitate decoding and behavior.iScience · 2023Article
- Synergistic population coding of natural communication stimuli by hindbrain electrosensory neurons.Scientific reports · 2021Article
- Population Coding of Natural Electrosensory Stimuli by Midbrain Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Neural Synchrony Gives Rise to Amplitude- and Duration-Invariant Encoding Consistent With Perception of Natural Communication Stimuli.Frontiers in neuroscience · 2020Article
- Encoding and Perception of Electro-communication Signals inFrontiers in integrative neuroscience · 2019Review
- Descending pathways generate perception of and neural responses to weak sensory input.PLoS biology · 2018Article
- Population Coding and Correlated Variability in Electrosensory Pathways.Frontiers in integrative neuroscience · 2018Review
- Differential receptive field organizations give rise to nearly identical neural correlations across three parallel sensory maps in weakly electric fish.PLoS computational biology · 2017Article
- Article
- Electrosensory neural responses to natural electro-communication stimuli are distributed along a continuum.PloS one · 2017Article
- Electrosensory processing in Apteronotus albifrons: implications for general and specific neural coding strategies across wave-type weakly electric fish species.Journal of neurophysiology · 2016Article
- Co-adaptation of electric organ discharges and chirps in South American ghost knifefishes (Apteronotidae).Journal of physiology, Paris · 2016Article
- Optimized Parallel Coding of Second-Order Stimulus Features by Heterogeneous Neural Populations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Adaptation to second order stimulus features by electrosensory neurons causes ambiguity.Scientific reports · 2016Article
- Neural correlations enable invariant coding and perception of natural stimuli in weakly electric fish.eLife · 2016Article
- Burst Firing in the Electrosensory System of Gymnotiform Weakly Electric Fish: Mechanisms and Functional Roles.Frontiers in computational neuroscience · 2016Review
- Contrast coding in the electrosensory system: parallels with visual computation.Nature reviews. Neuroscience · 2015Review
- Article
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4 authors.
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Abstract
Neurons that respond selectively but in an invariant manner to a given feature of natural stimuli have been observed across species and systems. Such responses emerge in higher brain areas, thereby suggesting that they occur by integrating afferent input. However, the mechanisms by which such integration occurs are poorly understood. Here we show that midbrain electrosensory neurons can respond selectively and in an invariant manner to heterogeneity in behaviorally relevant stimulus waveforms. Such invariant responses were not seen in hindbrain electrosensory neurons providing afferent input to these midbrain neurons, suggesting that response invariance results from nonlinear integration of such input. To test this hypothesis, we built a model based on the Hodgkin-Huxley formalism that received realistic afferent input. We found that multiple combinations of parameter values could give rise to invariant responses matching those seen experimentally. Our model thus shows that there are multiple solutions towards achieving invariant responses and reveals how subthreshold membrane conductances help promote robust and invariant firing in response to heterogeneous stimulus waveforms associated with behaviorally relevant stimuli. We discuss the implications of our findings for the electrosensory and other systems.
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