Evidence map›Paper›PMID 26473983›Full record

ArticleProteins2016

Some of the most interesting CASP11 targets through the eyes of their authors.

Andriy Kryshtafovych, John Moult, Arnaud Baslé, Alex Burgin, Timothy K Craig, Robert A Edwards, Deborah Fass, Marcus D Hartmann, Mateusz Korycinski, Richard J Lewis and 14 more

Open access · hybridAbstract read
In one paragraph

Article in Proteins, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 15 institutions in 7 countries.

Andriy KryshtafovychGenome Center, University of California, Davis, California, 95616.
John MoultDepartment of Cell Biology and Molecular Genetics, Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, Maryland, 20850.
Arnaud BasléInstitute for Cell and Molecular Biosciences, University of Newcastle, Newcastle upon Tyne, NE2 4HH, United Kingdom.
Alex BurginBroad Institute, Cambridge, Massachusetts, 02142.
Timothy K CraigTimPharma, Santa Clarita, California, 91350.
Robert A EdwardsDepartment of Biology, San Diego State University, San Diego, California, 92182.
Deborah FassDepartment of Structural Biology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Marcus D HartmannDepartment of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, 72076, Germany.
Mateusz KorycinskiDepartment of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, 72076, Germany.
Richard J LewisInstitute for Cell and Molecular Biosciences, University of Newcastle, Newcastle upon Tyne, NE2 4HH, United Kingdom.
Donald LorimerBeryllium, Bainbridge Island, Washington D.C, 98110.
Andrei N LupasDepartment of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, 72076, Germany.
Janet NewmanBiomedical Manufacturing Program, CSIRO, Parkville, VIC, Australia.
Thomas S PeatBiomedical Manufacturing Program, CSIRO, Parkville, VIC, Australia.
Kurt H PiepenbrinkInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, 21201.
Janani PrahladDepartment of Biochemistry and Redox Biology Center, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588.
Mark J van RaaijCentro Nactional De Biotecnologia (CNB-CSIC), Madrid, E-28049, Spain.
Forest RohwerDepartment of Biology and Viral Information Institute, San Diego State University, San Diego, California, 92182.
Anca M SegallDepartment of Biology and Viral Information Institute, San Diego State University, San Diego, California, 92182.
Victor SeguritanHuman Longevity Inc, La Jolla, California, 92121.
Eric J SundbergInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, 21201.
Abhimanyu K SinghSchool of Biosciences, University of Kent, Canterbury, Kent, United Kingdom.
Mark A WilsonDepartment of Biochemistry and Redox Biology Center, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588.
Torsten SchwedeBiozentrum, University of Basel, Basel, 4056, Switzerland. Torsten.Schwede@unibas.ch.
Max Planck Institute for Developmental Biology · DESan Diego State University · USCSIRO Manufacturing · AUNewcastle University · GBUniversity of Maryland, Baltimore · USUniversity of Nebraska–Lincoln · USAdvanced Bioscience Laboratories (United States) · USBeryllium (United States) · USBroad Institute · USCentro Nacional de Biotecnología · ESHuman Longevity (United States) · USUniversity of Basel · CHUniversity of California, Davis · USUniversity of Kent · GBWeizmann Institute of Science · IL

Funding

Prospective analysis to determine model accuracy performance and boundaries in the post-AlphaFold2 environmentR01GM100482 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIDELIS, KRZYSZTOF A · 2012 to 2025
$11.1M
Signaling Pathways in Innate ImmunityT32AI095190 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Stefanie N. Vogel · 2012 to 2026
$4.7M
Redox Biology CenterP30GM103335 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI BECKER, DONALD F · 2012 to 2016
$4.3M
Structure & Function of Clostridium difficile Type IV PiliR01AI114902 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SUNDBERG, ERIC JOHN · 2015 to 2019
$2.6M
NIAID NIH HHS R01 AI114902NIAID NIH HHS T32 AI095190NIGMS NIH HHS P30 GM103335NIGMS NIH HHS R01 GM100482
6 · The paper itself

Abstract

The Critical Assessment of protein Structure Prediction (CASP) experiment would not have been possible without the prediction targets provided by the experimental structural biology community. In this article, selected crystallographers providing targets for the CASP11 experiment discuss the functional and biological significance of the target proteins, highlight their most interesting structural features, and assess whether these features were correctly reproduced in the predictions submitted to CASP11. Proteins 2016; 84(Suppl 1):34-50. © 2015 The Authors. Proteins: Structure, Function, and Bioinformatics Published by Wiley Periodicals, Inc.

Indexed as

Models, MolecularModels, StatisticalSoftwareBacteriaComputational BiologyComputer GraphicsCrystallography, X-RayDatabases, ProteinHumansInternational CooperationProtein FoldingProtein Interaction Domains and MotifsProtein MultimerizationProteinsProtein Structure, SecondarySequence Homology, Amino AcidProteinsCASPNMRprotein structure predictionX-ray crystallography

Identifiers

PMID26473983
PMCPMC4834066
OpenAlexW2176189479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.