Evidence map›Paper›PMID 26473824›Full record

ArticleMolecules (Basel, Switzerland)2015

Antimicrobial Activity of Rhoeo discolor Phenolic Rich Extracts Determined by Flow Cytometry.

Rebeca García-Varela, Rebeca M García-García, Bertha A Barba-Dávila, Oscar R Fajardo-Ramírez, Sergio O Serna-Saldívar, Guy A Cardineau

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Phytochemical Characterization and Toxicity Activity ofMolecules (Basel, Switzerland) · 2026
    Article
  2. Preclinical Evaluation ofMolecules (Basel, Switzerland) · 2026
    Article
  3. Identification ofBiomolecules · 2025
    Article
  4. Neuroprotective effects ofJournal of traditional and complementary medicine · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Recent Advances in Plant Phenolics.Molecules (Basel, Switzerland) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rebeca García-VarelaCentro de Biotecnología FEMSA, Tecnologico de Monterrey, Campus Monterrey, Ave Eugenio Garza Sada 2501, Monterrey 64849, N.L., Mexico. rbk_varela@hotmail.com.
Rebeca M García-GarcíaCentro de Biotecnología FEMSA, Tecnologico de Monterrey, Campus Monterrey, Ave Eugenio Garza Sada 2501, Monterrey 64849, N.L., Mexico. rebeca.garcia.garcia@itesm.mx.
Bertha A Barba-DávilaCentro de Biotecnología FEMSA, Tecnologico de Monterrey, Campus Monterrey, Ave Eugenio Garza Sada 2501, Monterrey 64849, N.L., Mexico. bertha.barba@itesm.mx.
Oscar R Fajardo-RamírezCentro de Innovación y Transferida en Salud, Escuela de Medicina, Tecnologico de Monterrey, Campus Monterrey, Ave Morones Prieto No. 3000 Pte., Col. Los Doctores, C.P. Monterrey 64710, N.L., Mexico. ofajardo@itesm.mx.
Sergio O Serna-SaldívarCentro de Biotecnología FEMSA, Tecnologico de Monterrey, Campus Monterrey, Ave Eugenio Garza Sada 2501, Monterrey 64849, N.L., Mexico. sserna@itesm.mx.
Guy A CardineauCentro de Biotecnología FEMSA, Tecnologico de Monterrey, Campus Monterrey, Ave Eugenio Garza Sada 2501, Monterrey 64849, N.L., Mexico. Guy.Cardineau@itesm.mx.
Tecnológico de Monterrey · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional medicine has led to the discovery of important active substances used in several health-related areas. Phytochemicals in Rhoeo discolor extracts have proven to have important antimicrobial activity. In the present study, our group determined the antimicrobial effects of extracts of Rhoeo discolor, a plant commonly used in Mexico for both medicinal and ornamental purposes. We evaluated the in vitro activity of phenolic rich extracts against specifically chosen microorganisms of human health importance by measuring their susceptibility via agar-disc diffusion assay and flow cytometry: Gram-positive Listeria innocua and Streptococcus mutans, Gram-negative Escherichia coli and Pseudomonas aeruginosa, and lastly a fungal pathogen Candida albicans. Ten different extracts were tested in eight different doses on all the microorganisms. Analytical data revealed a high content of phenolic compounds. Both agar-disc diffusion assay and flow cytometry results demonstrated that Pseudomonas aeruginosa was the least affected by extract exposure. However, low doses of these extracts (predominantly polar), in a range from 1 to 4 μg/mL, did produce a statistically significant bacteriostatic and bactericidal effect on the rest of the microorganisms. These results suggest the addition of certain natural extracts from Rhoeo discolor could act as antibacterial and antimycotic drugs or additives for foods and cosmetics.

Indexed as

Anti-Bacterial AgentsAntifungal AgentsCandida albicansEscherichia coliListeriaMicrobial Sensitivity TestsPhenolsPlant ExtractsPlant LeavesPseudomonas aeruginosaSolventsStreptococcus mutansTradescantiaAnti-Bacterial AgentsAntifungal AgentsPhenolsPlant ExtractsSolventsantifungalantimicrobialCandida albicansEscherichia coliflow cytometryListeria innocuaphenolic compoundsPseudomonas aeruginosaRhoeo discolorStreptococcus mutans

Identifiers

PMID26473824
PMCPMC6331916
OpenAlexW1961044040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.