Evidence map›Paper›PMID 26473350›Full record

ArticleComparative medicine2015

Multicenter Safety and Immunogenicity Trial of an Attenuated Measles Vaccine for NHP.

Joann L Yee, NPRC Breeding Colony Management Consortium, Michael B McChesney, Kari L Christe

Abstract readMulticenter Study
In one paragraph

Article in Comparative medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Modified Dose Efficacy Trial of a Canine Distemper-Measles Vaccine for Use in Rhesus Macaques (Journal of the American Association for Laboratory Animal Science : JAALAS · 2019
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joann L YeeCalifornia National Primate Research Center, University of California, Davis, California, USA. joyee@ucdavis.edu.
NPRC Breeding Colony Management Consortium
Michael B McChesneyCalifornia National Primate Research Center, University of California, Davis, California, USA.
Kari L ChristeCalifornia National Primate Research Center, University of California, Davis, California, USA.

Funding

Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8M
National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
NIH HHS P51 OD010425NIH HHS P51OD010425NIH HHS P51 OD011104NIH HHS P51 OD011106NIH HHS P51OD011106NIH HHS P51 OD011107NIH HHS P51OD011107NIH HHS P51 OD011133NIH HHS P51OD011133PHS HHS P510D011132PHS HHS P51ODO11104
6 · The paper itself

Abstract

Measles is a highly contagious viral disease in NHP. The infection can range from asymptomatic to rapidly fatal, resulting in significant morbidity and mortality in captive populations. In addition to appropriate quarantine practices, restricted access, the immunization of all personnel in contact with NHP, and the wearing of protective clothing including face masks, measles immunization further reduces the infection risk. Commercially available measles vaccines are effective for use in NHP, but interruptions in their availability have prevented the implementation of ongoing, consistent vaccination programs. This need for a readily available vaccine led us to perform a broad, multicenter safety and immunogenicity study of another candidate vaccine, MVac (Serum Institute of India), a monovalent measles vaccine derived from live Edmonston-Zagreb strain virus that had been attenuated after 22 passages on human diploid cells.

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralFemaleImmunization ScheduleMacaca mulattaMacaca nemestrinaMaleMeaslesMeasles VaccineMeasles virusMonkey DiseasesSerologic TestsTime FactorsUnited StatesVaccines, AttenuatedAntibodies, NeutralizingAntibodies, ViralMeasles VaccineVaccines, Attenuated

Identifiers

PMID26473350
PMCPMC4617337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.