Evidence map›Paper›PMID 26473102›Full record

ArticleAnesthesiology and pain medicine2015

Do the Concentration and Volume of Local Anesthetics Affect the Onset and Success of Infraclavicular Anesthesia?

Faramarz Mosaffa, Babak Gharaei, Mohammad Qoreishi, Sajjad Razavi, Farhad Safari, Mohammad Fathi, Gholamreza Mohseni, Hedayatollah Elyasi, Fahimeh Hosseini

Registry-linked trialAbstract read
In one paragraph

Article in Anesthesiology and pain medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02820688 (Impact of Local Anesthetic Concentration-Volume Modifications on Ultrasound Guided Infraclavicular Nerve Block Effectiveness), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02820688 phase4completednot on this mapstarted 2016, after this paper: background citation

Impact of Local Anesthetic Concentration-Volume Modifications on Ultrasound Guided Infraclavicular Nerve Block Effectiveness

TypeinterventionalSponsorBozyaka Training and Research HospitalRan2016 to 2016Enrolled81ConditionsBrachial Plexus BlockadeArmsBupivacaine 0.25%, Prilocaine 1%, Infraclavicular Nerve Block, Bupivacaine 0.167%, Bupivacaine 0.125%
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Faramarz MosaffaAnesthesiology and Critical Care Department, Akhtar Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Babak GharaeiAnesthesiology and Critical Care Department, Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad QoreishiOrthopedic Department, Akhtar Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sajjad RazaviAnesthesiology and Critical Care Department, Mofid Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Farhad SafariAnesthesiology and Critical Care Department, Loghmane Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad FathiAnesthesiology Research Center, Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Gholamreza MohseniAnesthesiology and Critical Care Department, Akhtar Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hedayatollah ElyasiAnesthesiology and Critical Care Department, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fahimeh HosseiniAnesthesiology and Critical Care Department, Akhtar Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough local anesthesia is a suitable method for upper limb surgeries, there is debate regarding the effects of appropriate dosing.

objectivesIn the current study, we investigated the effects of the concentration and volume of a local anesthetic on the beginning and quality of anesthesia during upper limb orthopedic surgeries. PATIENTS AND

methodsThis double-blinded, randomized, clinical trial was conducted on 60 patients aged between 18 and 85 years candidated for upper limb orthopedic operations. The patients were equally and randomly distributed into two groups (n = 30). Under ultrasound imaging guidance, the first group received 7 mL of 2% lidocaine and the second group 10 mL of 1.3% lidocaine into the brachial plexus cords. The onset of block and the level of sensory and motor block were documented for each nerve territory.

resultsThe onset of sensory and motor block was significantly shorter in the 1.3% lidocaine group than in the 2% lidocaine group (P ≤ 0.05). The success rate of sensory and motor block was not different. The quality (completeness) of sensory block for the musculocutaneous nerve and that of motor block for the radial nerve were significantly better in the 1.3% lidocaine group than in the 2% lidocaine group.

conclusionsThe volume of the injected anesthetic accelerated the onset of sensory and motor block without affecting the rate of success in our patients.

Indexed as

Anesthesia, LocalAnestheticsBrachial PlexusLidocaineNerve Block

Identifiers

PMID26473102
PMCPMC4602380

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.