ArticleScientific reports2015
Microscopic Haematuria and Clinical Outcomes in Patients With Stage 3-5 Nondiabetic Chronic Kidney Disease.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Risk factors for progression of chronic kidney disease in the EPPIC trials and the effect of AST-120.Clinical and experimental nephrology · 2018Trial
- [Progression inhibition in chronic kidney disease].Innere Medizin (Heidelberg, Germany) · 2026Review
- Persistent Haematuria Is Associated With Reduced Kidney Survival in Primary Podocytopathies.Nephrology (Carlton, Vic.) · 2026Article
- Routine urinalysis for early clinical assessment in patients with vegetation-like echocardiographic findings.BMC infectious diseases · 2026Article
- Association Between Microscopic Hematuria and Proteinuria Remission in Adult Nephrotic Syndrome.Kidney medicine · 2026Article
- Diagnosis of Chronic Kidney Disease Using Retinal Imaging and Urine Dipstick Data: Multimodal Deep Learning Approach.JMIR medical informatics · 2025Article
- Asymptomatic hematuria in children: Korean Society of Pediatric Nephrology recommendations for diagnosis and management.Kidney research and clinical practice · 2024Article
- Practice facilitation for scale up of clinical decision support for hypertension management: study protocol for a cluster randomized control trial.Contemporary clinical trials · 2023Article
- Machine-learning enhancement of urine dipstick tests for chronic kidney disease detection.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Association between microscopic hematuria and albuminuria in patients with chronic kidney disease caused by diabetes and hypertension: the Fukuoka Kidney disease Registry Study.Clinical and experimental nephrology · 2023Article
- The application of new complex indicators in the detection of urine.BMC nephrology · 2023Article
- Automated urine sediment analyzers underestimate the severity of hematuria in glomerular diseases.Scientific reports · 2021Article
- Higher cardiovascular mortality in men with persistent dipstick hematuria.Clinical and experimental nephrology · 2021Article
- Hematuria as a risk factor for progression of chronic kidney disease and death: findings from the Chronic Renal Insufficiency Cohort (CRIC) Study.BMC nephrology · 2018Article
- Diabetic Retinopathy and Clinical Parameters Favoring the Presence of Diabetic Nephropathy could Predict Renal Outcome in Patients with Diabetic Kidney Disease.Scientific reports · 2017Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Microscopic haematuria is proposed as a prognostic factor for renal outcomes in patients with glomerulonephritis. However, the role of haematuria in patients with advanced chronic kidney disease (CKD) or heavy proteinuria has not been investigated. We divided 1799 patients with stage 3-5 nondiabetic CKD into 3 groups according to the results from 3 urinalyses: no haematuria (0-2 red blood cells [RBCs]/hpf ≥2 times), mild haematuria (2-5 RBCs/hpf ≥2 times) and moderate haematuria (≥5-10 RBCs/hpf ≥2 times). The estimated glomerular filtration rate was 25.4 mL/min/1.73 m(2), with a urine protein-to-creatinine ratio (UPCR) of 881 mg/g. The hazard ratios (HRs) of mild and moderate haematuria for end-stage renal disease (ESRD) were 1.28 (95% confidence interval [CI]: 1.05-1.56, P = 0.024) and 1.34 (95% CI: 1.03-1.74, P = 0.030), respectively. The HR of moderate haematuria for mortality was 1.56 (95% CI: 1.11-2.20, P = 0.011). According to subgroup analysis, the HR of moderate haematuria for ESRD in patients with a UPCR of <500 mg/g was more prominent than that in patients with a UPCR of ≥500 mg/g. Microscopic haematuria in patients with stage 3-5 nondiabetic CKD is associated with increased risks of ESRD and mortality.
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