ArticleScientific reports2015
Domestication Effects on Stress Induced Steroid Secretion and Adrenal Gene Expression in Chickens.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Effects of Maternal Omega-3 Supplementation, Sex, and Strain on Chick Behaviour During Social Isolation.Animals : an open access journal from MDPI · 2026Article
- Gene Expression of Feed Intake-Regulating Peptides in the Gut-Brain Axis of Laying Hens Housed Under Two Different Egg Production Systems.Animals : an open access journal from MDPI · 2025Article
- The genomics of the domestication syndrome in a songbird model species.Communications biology · 2025Article
- The quantitative anatomy of the hippocampal formation in homing pigeons and other pigeon breeds: implications for spatial cognition.Brain structure & function · 2024Article
- Exploring Evolutionary Adaptations and Genomic Advancements to Improve Heat Tolerance in Chickens.Animals : an open access journal from MDPI · 2024Review
- Robust identification of interactions between heat-stress responsive genes in the chicken brain using Bayesian networks and augmented expression data.Scientific reports · 2024Article
- Circadian Corticosterone Profile in Laying Hens (Animals : an open access journal from MDPI · 2024Article
- Association of tameness and sociability but no sign of domestication syndrome in mice selectively bred for active tameness.Genes, brain, and behavior · 2024Article
- Effects of vitamin C and early-age thermal conditioning on pituitary adrenocorticotropic hormone cells in broilers chronically exposed to heat stress: an immunohistomorphometric and hormonal study.Veterinary research forum : an international quarterly journal · 2024Article
- Association between Temperament and Stress-related Gene Expression in Day-old Chickens.The journal of poultry science · 2024Article
- A Preliminary Study on the Interplay between the Serum Levels of Neurotransmitters and Thyroid Hormones for the Evaluation of the Behavioral Phenotype of Dogs.Animals : an open access journal from MDPI · 2023Article
- Traditional sexing methods and external egg characteristics combination allow highly accurate early sex determination in an endangered native turkey breed.Frontiers in veterinary science · 2022Article
- Effects of acute heat stress on protein expression and histone modification in the adrenal gland of male layer-type country chickens.Scientific reports · 2021Article
- HPLC MS-MS Analysis Shows Measurement of Corticosterone in Egg Albumen Is Not a Valid Indicator of Chicken Welfare.Animals : an open access journal from MDPI · 2020Article
- Physical and Physiological Indicators of Welfare in Guinea Pigs (Animals : an open access journal from MDPI · 2020Article
- Avian Physiology: Are Birds Simply Feathered Mammals?Frontiers in physiology · 2020Review
- Putative Epigenetic Biomarkers of Stress in Red Blood Cells of Chickens Reared Across Different Biomes.Frontiers in genetics · 2020Article
- Sexual Dimorphism for Coping Styles Complements Traditional Methods for Sex Determination in a Multivariety Endangered Hen Breed.Animals : an open access journal from MDPI · 2019Article
- Unpredictable Chronic Mild Stress Suppresses the Incorporation of New Neurons at the Caudal Pole of the Chicken Hippocampal Formation.Scientific reports · 2019Article
- Interactions Between Gut Microbiota and Acute Restraint Stress in Peripheral Structures of the Hypothalamic-Pituitary-Adrenal Axis and the Intestine of Male Mice.Frontiers in immunology · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the genetic basis of phenotypic diversity is a challenge in contemporary biology. Domestication provides a model for unravelling aspects of the genetic basis of stress sensitivity. The ancestral Red Junglefowl (RJF) exhibits greater fear-related behaviour and a more pronounced HPA-axis reactivity than its domesticated counterpart, the White Leghorn (WL). By comparing hormones (plasmatic) and adrenal global gene transcription profiles between WL and RJF in response to an acute stress event, we investigated the molecular basis for the altered physiological stress responsiveness in domesticated chickens. Basal levels of pregnenolone and dehydroepiandrosterone as well as corticosterone response were lower in WL. Microarray analysis of gene expression in adrenal glands showed a significant breed effect in a large number of transcripts with over-representation of genes in the channel activity pathway. The expression of the best-known steroidogenesis genes were similar across the breeds used. Transcription levels of acute stress response genes such as StAR, CH25 and POMC were upregulated in response to acute stress. Dampened HPA reactivity in domesticated chickens was associated with changes in the expression of several genes that presents potentially minor regulatory effects rather than by means of change in expression of critical steroidogenic genes in the adrenal.
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