Evidence map›Paper›PMID 26471265›Full record

SynthesisJournal of the International AIDS Society2015

Uptake and yield of HIV testing and counselling among children and adolescents in sub-Saharan Africa: a systematic review.

Darshini Govindasamy, Rashida A Ferrand, Stephanie Ms Wilmore, Nathan Ford, Saeed Ahmed, Hoviyeh Afnan-Holmes, Katharina Kranzer

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Journal of the International AIDS Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 2 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 2 syntheses or guidelines pooled it, 116 citations in OpenAlex.

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  3. HIV Care Cascade Among Adolescents in a "Test and Treat" Community-Based Intervention: HPTN 071 (PopART) for Youth Study.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2021
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  5. Financial Incentives for Pediatric HIV Testing in Kenya.The Pediatric infectious disease journal · 2018
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

Darshini GovindasamyHealth Systems Research Unit, South African Medical Research Council, Cape Town, South Africa; gdarsh@gmail.com.
Rashida A FerrandDepartment of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Stephanie Ms WilmoreCentre for Clinical Microbiology, University College London, London, United Kingdom.
Nathan FordHIV/AIDS Department, World Health Organization, Geneva, Switzerland.
Saeed AhmedTingathe Outreach Program, Baylor College of Medicine Children's Foundation Malawi, Lilongwe, Malawi.
Hoviyeh Afnan-HolmesDepartment of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Katharina KranzerDepartment of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.
London School of Hygiene & Tropical Medicine · GBBaylor College of Medicine · USSouth African Medical Research Council · ZAUniversity College London · GBWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionIn recent years children and adolescents have emerged as a priority for HIV prevention and care services. We conducted a systematic review to investigate the acceptability, yield and prevalence of HIV testing and counselling (HTC) strategies in children and adolescents (5 to 19 years) in sub-Saharan Africa.

methodsAn electronic search was conducted in MEDLINE, EMBASE, Global Health and conference abstract databases. Studies reporting on HTC acceptability, yield and prevalence and published between January 2004 and September 2014 were included. Pooled proportions for these three outcomes were estimated using a random effects model. A quality assessment was conducted on included studies. RESULTS AND DISCUSSION: A total of 16,380 potential citations were identified, of which 21 studies (23 entries) were included. Most studies were conducted in Kenya (n=5) and Uganda (n=5) and judged to provide moderate (n=15) to low quality (n=7) evidence, with data not disaggregated by age. Seven studies reported on provider-initiated testing and counselling (PITC), with the remainder reporting on family-centred (n=5), home-based (n=5), outreach (n=5) and school-linked HTC among primary schoolchildren (n=1). PITC among inpatients had the highest acceptability (86.3%; 95% confidence interval [CI]: 65.5 to 100%), yield (12.2%; 95% CI: 6.1 to 18.3%) and prevalence (15.4%; 95% CI: 5.0 to 25.7%). Family-centred HTC had lower acceptance compared to home-based HTC (51.7%; 95% CI: 10.4 to 92.9% vs. 84.9%; 95% CI: 74.4 to 95.4%) yet higher prevalence (8.4%; 95% CI: 3.4 to 13.5% vs. 3.0%; 95% CI: 1.0 to 4.9%). School-linked HTC showed poor acceptance and low prevalence.

conclusionsWhile PITC may have high test acceptability priority should be given to evaluating strategies beyond healthcare settings (e.g. home-based HTC among families) to identify individuals earlier in their disease progression. Data on linkage to care and cost-effectiveness of HTC strategies are needed to strengthen policies.

Indexed as

CounselingAdolescentAdultAfrica South of the SaharaChildHIV InfectionsHumansadolescentschildrenHIV testing and counsellingsub-Saharan Africa

Identifiers

PMID26471265
PMCPMC4607700
OpenAlexW1913337589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.