ArticleThe journal of headache and pain2015
Headache as a predictor for dementia: The HUNT Study.
Article in The journal of headache and pain, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 7 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 7 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Chronic Pain and the Risk of Dementia: A Systematic Review and Meta-Analysis.Current pain and headache reports · 2026Pooled it
- Chronic pain and risk of cognitive impairment: a meta-analysis of longitudinal cohort studies.Translational psychiatry · 2026Pooled it
- Is headache a risk factor for dementia? A systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Pooled it
- Migraine and the risk of dementia: a meta-analysis and systematic review.Aging clinical and experimental research · 2022Pooled it
- Association of Headache Disorders and the Risk of Dementia: Meta-Analysis of Cohort Studies.Frontiers in aging neuroscience · 2022Pooled it
- The Potential Contribution of Chronic Pain and Common Chronic Pain Conditions to Subsequent Cognitive Decline, New Onset Cognitive Impairment, and Incident Dementia: A Systematic Review and Conceptual Model for Future Research.Journal of Alzheimer's disease : JAD · 2020Pooled it
- Headache disorder and the risk of dementia: a systematic review and meta-analysis of cohort studies.The journal of headache and pain · 2018Pooled it
- Increased Risk of Dementia in Patients with Tension-Type Headache: A Nationwide Retrospective Population-Based Cohort Study.PloS one · 2016Trial
- Independent causal effect of migraines on Alzheimer's disease risk: a multivariate Mendelian randomization study.Frontiers in neurology · 2024Article
- Cognitive Impairment in Primary and Secondary Headache Disorders.Current pain and headache reports · 2022Review
- Review
- Mid- to late-life migraine diagnoses and risk of dementia: a national register-based follow-up study.The journal of headache and pain · 2020Article
- Non-Cancer Chronic Pain Conditions and Risk for Incident Alzheimer's Disease and Related Dementias in Community-Dwelling Older Adults: A Population-Based Retrospective Cohort Study of United States Medicare Beneficiaries, 2001-2013.International journal of environmental research and public health · 2020Article
- The Association of Osteoarthritis and Related Pain Burden to Incident Alzheimer's Disease and Related Dementias: A Retrospective Cohort Study of U.S. Medicare Beneficiaries.Journal of Alzheimer's disease : JAD · 2020Article
- Age-specific and gender-dependent impact of primary headache disorders on dementia risk: Population-based longitudinal study.Medicine · 2018Article
- Increased risk of Parkinson's disease following tension-type headache: a nationwide population-based cohort study.Oncotarget · 2018Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe impact of headache on dementia is largely unknown. This study examined the association between headache and dementia using data from a large population-based study.
methodsThis population-based study used data from the Nord-Trøndelag Health Surveys performed in 1995-1997 (HUNT2) and 2006-2008 (HUNT3). The reference group (controls) was participants aged ≥55 years who answered the headache questions in HUNT2 and later participated in HUNT3 (n = 15,601). The association with headache status in HUNT2 was investigated in sample of confirmed non-demented elderly evaluated with psychometric tests after HUNT3 (n = 96), and HUNT2 participants later diagnosed with dementia during 1997-2011 (n = 746). The association with headache was evaluated by logistical regression with adjustment for age, gender, level of education, comorbidity, smoking, and anxiety and depression.
resultsAny headache was more likely to be reported in HUNT2 among those who later were included in the dementia registry (OR 1.24; 95 % CI 1.04-1.49) compared to the reference group, but less likely among the confirmed non-demented individuals (OR 0.62; 95 % CI 0.39-0.98). This relationship was even stronger for non-migrainous headache, whereas such association was not found for migraine.
conclusionsCompared to the reference group, individuals with dementia were more likely to report non-previous migrainous headache in HUNT2, whereas a sample of confirmed non-demented were less likely to report previous non-migrainous headache.
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