Evidence map›Paper›PMID 26471159›Full record

Trial reportAddiction (Abingdon, England)2015

Project QUIT (Quit Using Drugs Intervention Trial): a randomized controlled trial of a primary care-based multi-component brief intervention to reduce risky drug use.

Lillian Gelberg, Ronald M Andersen, Abdelmonem A Afifi, Barbara D Leake, Lisa Arangua, Mani Vahidi, Kyle Singleton, Julia Yacenda-Murphy, Steve Shoptaw, Michael F Fleming and 1 more

3 registry-linked trialsOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Addiction (Abingdon, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 43 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 5 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01942876 phase2 / phase3completednot on this map

Preventing Drug Use in Low Income Clinic Populations

TypeinterventionalSponsorUniversity of California, Los AngelesRan2011 to 2013Enrolled411ConditionsDrug Use, Harmful UseArmsQuit Using Drugs Intervention Trial, Health behavior maintenance
NCT04706624 nacompletednot on this mapstarted 2021, after this paper: background citation

Screen, Treat and Retain Meth-using People With Opioid Use Disorders at Methadone Clinics

TypeinterventionalSponsorHanoi Medical UniversityRan2021 to 2025Enrolled667ConditionsMethamphetamine Abuse, Opioid-use Disorder, HIV SeropositivityArmsContingency management (12 weeks), Contingency management (6 weeks), SMS reminders, Matrix only, Matrix + Contingency management
NCT04935606 nacompletednot on this mapstarted 2021, after this paper: background citation

mHealth to Enhance & Sustain Drug Use Reduction of the QUIT BI in Primary Care

TypeinterventionalSponsorUniversity of California, Los AngelesRan2021 to 2026Enrolled457ConditionsDrug UseArmsUsual Care, QUIT Intervention (doctor brief advice, video doctor, health coaching sessions at 2- and 6-weeks), QUIT-Mobile (QUIT Intervention plus weekly mobile-web app or text message weekly self-monitoring, automated feedback over 12 months)
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 5 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Investigating for Whom Brief Substance Use Interventions Are Most Effective: An Individual Participant Data Meta-analysis.Prevention science : the official journal of the Society for Prevention Research · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Lillian GelbergDavid Geffen School of Medicine at UCLA, Department of Family Medicine, Los Angeles, CA, USA.
Ronald M AndersenUniversity of California at Los Angeles, Fielding School of Public Health, Los Angeles, CA, USA.
Abdelmonem A AfifiUniversity of California at Los Angeles, Fielding School of Public Health, Los Angeles, CA, USA.
Barbara D LeakeDavid Geffen School of Medicine at UCLA, Department of Family Medicine, Los Angeles, CA, USA.
Lisa AranguaDavid Geffen School of Medicine at UCLA, Department of Family Medicine, Los Angeles, CA, USA.
Mani VahidiDavid Geffen School of Medicine at UCLA, Department of Family Medicine, Los Angeles, CA, USA.
Kyle SingletonUniversity of California at Los Angeles, Medical Imaging Informatics Group, Los Angeles, CA, USA.
Julia Yacenda-MurphyDavid Geffen School of Medicine at UCLA, Department of Family Medicine, Los Angeles, CA, USA.
Steve ShoptawDavid Geffen School of Medicine at UCLA, Department of Family Medicine, Los Angeles, CA, USA.
Michael F FlemingNorthwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Sebastian E BaumeisterDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Germany.
University of California, Los Angeles · USLos Angeles Medical Center · USNorthwestern University · USUniversity of Regensburg · DE

Funding

INNOVATIVE IMPLEMENTATION RESEARCH METHODS COREP30DA027828 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BROWN, C. HENDRICKS, MUSTANSKI, BRIAN · 2011 to 2020
$11.4M
Preventing Drug Use in Low Income Clinic PopulationsR01DA022445 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GELBERG, LILLIAN · 2008 to 2011
$1.8M
NIDA NIH HHS P30 DA027828NIDA NIH HHS R01 DA022445NIDA NIH HHS R01 DA022445-01
6 · The paper itself

Abstract

aimsTo assess the effect of a multi-component primary care delivered brief intervention for reducing risky psychoactive drug use (RDU) among patients identified by screening.

designMulticenter single-blind two-arm randomized controlled trial of patients enrolled from February 2011 to November 2012 with 3-month follow-up. Randomization and allocation to trial group were computer-generated.

settingPrimary care waiting rooms of five federally qualified health centers in Los Angeles County (LAC), USA.

participantsA total of 334 adult primary care patients (171 intervention; 163 control) with RDU scores (4-26) on the World Health Organization (WHO) Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) self-administered on tablet computers. 261 (78%) completed follow-up. Mean age was 41.7 years; 62.9% were male; 37.7% were Caucasian. INTERVENTION(S) AND MEASUREMENT: Intervention patients received brief (typically 3-4 minutes) clinician advice to quit/reduce their drug use reinforced by a video doctor message, health education booklet and up to two 20-30-minute follow-up telephone drug use coaching sessions. Controls received usual care and cancer screening information. Primary outcome was patient self-reported use of highest scoring drug (HSD) at follow-up.

findingsIntervention and control patients reported equivalent baseline HSD use at 3-month follow-up. After adjustment for covariates, in the complete sample linear regression model, intervention patients used their HSD on 3.5 fewer days in the previous month relative to controls (P<0.001), and in the completed sample model, intervention patients used their HSD 2.2 fewer days than controls (P < 0.005). No compensatory increases in use of other measured substances were found.

conclusionsA primary-care based, clinician-delivered brief intervention with follow-up coaching calls may decrease risky psychoactive drug use.

Indexed as

Primary Health CareAdultCognitive Behavioral TherapyFemaleHumansLos AngelesMaleMiddle AgedMotivational InterviewingPamphletsPatient Education as TopicPsychotherapy, BriefSingle-Blind MethodSubstance-Related DisordersTelephoneVideo RecordingBrief interventioncommunity health centersmotivational interviewingprimary carerandomized controlled trialrisky drug use

Identifiers

PMID26471159
PMCPMC4948983
OpenAlexW1926530492

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.