ArticleJournal of magnetic resonance imaging : JMRI2016
Interplatform reproducibility of liver and spleen stiffness measured with MR elastography.
Article in Journal of magnetic resonance imaging : JMRI, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Repeatability of MR Elastography of Liver: A Meta-Analysis.Radiology · 2017Pooled it
- Comparative Precision of 3D MRE and 2D MRE for Measurement of Liver Stiffness in Adults with Severe Obesity.Radiology · 2026Article
- Detecting decompensation in cirrhotic patients with varying ascitic volumes using magnetic resonance elastography.Abdominal radiology (New York) · 2026Article
- Simple Clinical Prediction Rules for Identifying Significant Liver Fibrosis: Evaluation of Established Scores and Development of the Aspartate Aminotransferase-Thrombocytopenia-Albumin (ATA) Score.Diagnostics (Basel, Switzerland) · 2025Article
- 3D MR elastography at 0.55 T: Concomitant field effects and feasibility.Magnetic resonance in medicine · 2025Article
- Magnetic Resonance Elastography of Upper Trapezius Muscle.NMR in biomedicine · 2025Article
- Precision and Test-Retest Repeatability of Stiffness Measurement with MR Elastography: A Multicenter Phantom Study.Radiology · 2024Article
- Preoperative Magnetic Resonance Elastography (MRE) of Skull Base Tumours: A Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Evaluation of Spleen Stiffness in Young Healthy Volunteers Using Magnetic Resonance Elastography.Diagnostics (Basel, Switzerland) · 2023Article
- Multiparametric MR assessment of liver fat, iron, and fibrosis: a concise overview of the liver "Triple Screen".Abdominal radiology (New York) · 2023Review
- Liver fibrosis assessment: MR and US elastography.Abdominal radiology (New York) · 2022Review
- Noninvasive staging of liver fibrosis: review of current quantitative CT and MRI-based techniques.Abdominal radiology (New York) · 2022Review
- Liver Fibrosis: Counterpoint-MR Elastography Is the Noninvasive Imaging Modality of Choice for Detecting and Staging Liver Fibrosis.AJR. American journal of roentgenology · 2022Article
- Development of three-dimensional integral-type reconstruction formula for magnetic resonance elastography.International journal of computer assisted radiology and surgery · 2021Article
- Evaluation of MR elastography for prediction of lymph node metastasis in prostate cancer.Abdominal radiology (New York) · 2021Article
- Diagnostic value of spleen stiffness by magnetic resonance elastography for prediction of esophageal varices in cirrhotic patients.Abdominal radiology (New York) · 2021Article
- MR elastography of liver: current status and future perspectives.Abdominal radiology (New York) · 2020Review
- Multiparametric MR mapping in clinical decision-making for diffuse liver disease.Abdominal radiology (New York) · 2020Review
- Noninvasive imaging assessment of portal hypertension.Abdominal radiology (New York) · 2020Review
- Magnetic resonance imaging for the assessment of pathological hepatic findings in nonalcoholic fatty liver disease.Journal of medical ultrasonics (2001) · 2020Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeTo assess interplatform reproducibility of liver stiffness (LS) and spleen stiffness (SS) measured with magnetic resonance elastography (MRE) based on a 2D gradient echo (GRE) sequence. MATERIALS AND
methodsThis prospective Health Insurance Portability and Accountability Act (HIPAA)-compliant and Institutional Review Board (IRB)-approved study involved 12 subjects (five healthy volunteers and seven patients with liver disease). A multislice 2D-GRE-based MRE sequence was performed using two systems from different vendors (3.0T GE and 1.5T Siemens) on the same day. Two independent observers measured LS and SS on confidence maps. Bland-Altman analysis (with coefficient of reproducibility, CR), coefficient of variability (CV), and intraclass correlation (ICC) were used to analyze interplatform, intra- and interobserver variability. Human data were validated using a gelatin-based phantom.
resultsThere was excellent reproducibility of phantom stiffness measurement (CV 4.4%). Mean LS values were 3.44-3.48 kPa and 3.62-3.63 kPa, and mean SS values were 7.54-7.91 kPa and 8.40-8.85 kPa at 3.0T and 1.5T for observers 1 and 2, respectively. The mean CVs between platforms were 9.2%-11.5% and 13.1%-14.4% for LS and SS, respectively, for observers 1 and 2. There was excellent interplatform reproducibility (ICC >0.88 and CR <36.2%) for both LS and SS, and excellent intra- and interobserver reproducibility (intraobserver: ICC >0.99, CV <2.1%, CR <6.6%; interobserver: ICC >0.97, CV and CR <16%).
conclusionThis study demonstrates that 2D-GRE MRE provides platform- and observer-independent LS and SS measurements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.