Evidence map›Paper›PMID 26469636›Full record

ArticleThe Analyst2015

Magnetic-optical nanohybrids for targeted detection, separation, and photothermal ablation of drug-resistant pathogens.

Thomas J Ondera, Ashton T Hamme

Abstract read
In one paragraph

Article in The Analyst, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Detection ofSensors (Basel, Switzerland) · 2020
    Article
  4. Article
  5. Carbon nanotubes as anti-bacterial agents.Cellular and molecular life sciences : CMLS · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Thomas J OnderaDepartment of Chemistry and Biochemistry, Jackson State University, 1400 J R Lynch street, Jackson, MS 39217, USA. ashton.t.hamme@jsums.edu.
Ashton T HammeDepartment of Chemistry and Biochemistry, Jackson State University, 1400 J R Lynch street, Jackson, MS 39217, USA. ashton.t.hamme@jsums.edu.
Jackson College · US

Funding

TRANSCRIPTOMICS OF GIARDIA LAMBLIAG12RR013459 · NCRR · JACKSON STATE UNIVERSITY · PI GAO, RUOMEI · 1998 to 2011
$18.0M
RCMI-Center for Environmental HealthG12MD007581 · NIMHD · JACKSON STATE UNIVERSITY · PI TCHOUNWOU, PAUL B. · 2012 to 2017
$11.2M
NCRR NIH HHS G12 RR013459NCRR NIH HHS G12RR013459NIMHD NIH HHS G12 MD007581NIMHD NIH HHS G12MD007581
6 · The paper itself

Abstract

A rapid, sensitive and quantitative immunoassay for the targeted detection and decontamination of E. coli based on Fe3O4 magnetic nanoparticles (MNPs) and plasmonic popcorn-shaped gold nanostructure attached single-walled carbon nanotubes (AuNP@SWCNT) is presented. The MNPs were synthesized as the support for a monoclonal antibody (mAb@MNP). E. coli (49979) was captured and rapidly preconcentrated from the sample with the mAb@MNP, followed by binding with Raman-tagged concanavalin A-AuNP@SWCNTs (Con A-AuNP@SWCNTs) as detector nanoprobes. A Raman tag 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) generated a Raman signal upon 670 nm laser excitation enabling the detection and quantification of E. coli concentration with a limit of detection of 10(2) CFU mL(-1) and a linear logarithmic response range of 1.0 × 10(2) to 1.0 × 10(7) CFU mL(-1). The mAb@MNP could remove more than 98% of E. coli (initial concentration of 1.3 × 10(4) CFU mL(-1)) from water. The potential of the immunoassay to detect E. coli bacteria in real water samples was investigated and the results were compared with the experimental results from the classical count method. There was no statistically significant difference between the two methods (p > 0.05). Furthermore, the MNP/AuNP@SWCNT hybrid system exhibits an enhanced photothermal killing effect. The sandwich-like immunoassay possesses potential for rapid bioanalysis and the simultaneous biosensing of multiple pathogenic agents.

Indexed as

Drug Resistance, MicrobialMagneticsBacteriaBacteriological TechniquesLimit of DetectionMicroscopy, Electron, TransmissionNanoparticlesOptics and PhotonicsTemperatureTime Factors

Identifiers

PMID26469636
PMCPMC4643457
OpenAlexW1885283541

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.