ArticleScientific reports2015
Quantification of Interfibrillar Shear Stress in Aligned Soft Collagenous Tissues via Notch Tension Testing.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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Who cites it
21 citing papers in PubMed.
- Sex Hormones & Exercise in the Musculoskeletal System: From Signaling to Structure and Function.Endocrine reviews · 2026Article
- Shear wave propagation as a noninvasive metric of loading and microdamage in tendon fascicles.Journal of the mechanical behavior of biomedical materials · 2025Article
- Neural network auto-segmentation of serial-block-face scanning electron microscopy images exhibit collagen fibril structural differences with tendon type and health.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Volume Loss and Recovery in Bovine Knee Meniscus Loaded in Circumferential Tension.Journal of biomechanical engineering · 2023Article
- Hierarchical ultrastructure: An overview of what is known about tendons and future perspective for tendon engineering.Bioactive materials · 2022Review
- Review
- Tear propagation in vaginal tissue under inflation.Acta biomaterialia · 2021Article
- Molecular origin of viscoelasticity in mineralized collagen fibrils.Biomaterials science · 2021Article
- Structure, function, and defect tolerance with maturation of the radial tie fiber network in the knee meniscus.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020Article
- Dependence of tendon multiscale mechanics on sample gauge length is consistent with discontinuous collagen fibrils.Acta biomaterialia · 2020Article
- Interfibrillar shear behavior is altered in aging tendon fascicles.Biomechanics and modeling in mechanobiology · 2020Article
- Multiscale composite model of fiber-reinforced tissues with direct representation of sub-tissue properties.Biomechanics and modeling in mechanobiology · 2020Article
- Helical fibrillar microstructure of tendon using serial block-face scanning electron microscopy and a mechanical model for interfibrillar load transfer.Journal of the Royal Society, Interface · 2019Article
- The impact of loading, unloading, ageing and injury on the human tendon.The Journal of physiology · 2019Review
- Load transfer, damage, and failure in ligaments and tendons.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018Review
- Short cracks in knee meniscus tissue cause strain concentrations, but do not reduce ultimate stress, in single-cycle uniaxial tension.Royal Society open science · 2018Article
- Freezing does not alter multiscale tendon mechanics and damage mechanisms in tension.Annals of the New York Academy of Sciences · 2017Article
- Evidence that interfibrillar load transfer in tendon is supported by small diameter fibrils and not extrafibrillar tissue components.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2017Article
- Investigating mechanisms of tendon damage by measuring multi-scale recovery following tensile loading.Acta biomaterialia · 2017Article
- Mechanical function near defects in an aligned nanofiber composite is preserved by inclusion of disorganized layers: Insight into meniscus structure and function.Acta biomaterialia · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The mechanical function of soft collagenous tissues is largely determined by their hierarchical organization of collagen molecules. While collagen fibrils are believed to be discontinuous and transfer load through shearing of the interfibrillar matrix, interfibrillar shear stresses have never been quantified. Scaling traditional shear testing procedures down to the fibrillar length scale is impractical and would introduce substantial artifacts. Here, through the use of a novel microscopic variation of notch tension testing, we explicitly demonstrate the existence of interfibrillar shear stresses within tendon fascicles and provide the first measurement of their magnitude. Axial stress gradients along the sample length generated by notch tension testing were measured and used to calculate a value of 32 kPa for the interfibrillar shear stress. This estimate is comparable to the interfibrillar shear stress predicted by previous multiscale modeling of tendon fascicles, which supports the hypothesis that fibrils are discontinuous and transmit load through interfibrillar shear. This information regarding the structure-function relationships of tendon and other soft collagenous tissues is necessary to identify potential causes for tissue impairment with degeneration and provide the foundation for developing regenerative repair strategies or engineering biomaterials for tissue replacement.
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