SynthesisPloS one2015
Use of Mesh in Laparoscopic Paraesophageal Hernia Repair: A Meta-Analysis and Risk-Benefit Analysis.
Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evidence mapping on how to perform an optimal surgical repair of large hiatal hernias.Langenbeck's archives of surgery · 2023Pooled it
- Systematic review and meta-analysis of laparoscopic mesh versus suture repair of hiatus hernia: objective and subjective outcomes.Surgical endoscopy · 2017Pooled it
- Acute gastric volvulus: optimal timing for repair?Surgical endoscopy · 2026Article
- Review
- Aortoenteric Fistula: An Uncommon but Life-Threatening Complication of Pledget Use in Hiatal Hernia Repair.Cureus · 2025Article
- Is mesh essential in laparoscopic hiatal hernia repair? analysis of 30-day outcomes from the ACS-NSQIP database over eight years.Frontiers in surgery · 2025Article
- ENDOSCOPIC MANAGEMENT OF MESH MIGRATION FOLLOWING HIATAL HERNIA REPAIR.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2024Article
- Determining the need for a thoracoscopic approach to treat a giant hiatal hernia when abdominal access is poor.World journal of gastrointestinal surgery · 2023Article
- Hiatus hernia repair with a new-generation biosynthetic mesh: a 4-year single-center experience.Surgical endoscopy · 2023Article
- Management of paraesophageal hiatus hernia: recommendations following a European expert Delphi consensus.Surgical endoscopy · 2023Article
- Laparoscopic posterior cruroplasty: a patient tailored approach.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- Trans-hiatal herniation following esophagectomy or gastrectomy: retrospective single-center experiences with a potential surgical emergency.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- Robot-assisted vs. laparoscopic repair of complete upside-down stomach hiatal hernia (the RATHER-study): a prospective comparative single center study.Surgical endoscopy · 2022Article
- Management of paraesophageal hernia review of clinical studies: timing to surgery, mesh use, fundoplication, gastropexy and other controversies.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2020Article
- Laparoscopic repair of a giant hiatal hernia after minimally invasive oesophagectomy.Annals of the Royal College of Surgeons of England · 2020Article
- What Is the Reality of Hiatal Hernia Management?-A Registry Analysis.Frontiers in surgery · 2020Article
- [Hiatus hernia : Standards and controversies in diagnostics and treatment].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2019Article
- Follow Up Data of MRI-Visible Synthetic Meshes for Reinforcement in Large Hiatal Hernia in Comparison to None-Mesh Repair-A Prospective Cohort Study.Frontiers in surgery · 2019Article
- Treatment of giant paraesophageal hernia: pro laparoscopic approach.Hernia : the journal of hernias and abdominal wall surgery · 2018Review
- A modified Nissen fundoplication: subjective and objective midterm results.Langenbeck's archives of surgery · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMesh augmentation seems to reduce recurrences following laparoscopic paraesophageal hernia repair (LPHR). However, there is an uncertain risk of mesh-associated complications. Risk-benefit analysis might solve the dilemma. MATERIALS AND
methodsA systematic literature search was performed to identify randomized controlled trials (RCTs) and observational clinical studies (OCSs) comparing laparoscopic mesh-augmented hiatoplasty (LMAH) with laparoscopic mesh-free hiatoplasty (LH) with regard to recurrences and complications. Random effects meta-analyses were performed to determine potential benefits of LMAH. All data regarding LMAH were used to estimate risk of mesh-associated complications. Risk-benefit analysis was performed using a Markov Monte Carlo decision-analytic model.
resultsMeta-analysis of 3 RCTs and 9 OCSs including 915 patients revealed a significantly lower recurrence rate for LMAH compared to LH (pooled proportions, 12.1% vs. 20.5%; odds ratio (OR), 0.55; 95% confidence interval (CI), 0.34 to 0.89; p = 0.04). Complication rates were comparable in both groups (pooled proportions, 15.3% vs. 14.2%; OR, 1.02; 95% CI, 0.63 to 1.65; p = 0.94). The systematic review of LMAH data yielded a mesh-associated complication rate of 1.9% (41/2121; 95% CI, 1.3% to 2.5%) for those series reporting at least one mesh-associated complication. The Markov Monte Carlo decision-analytic model revealed a procedure-related mortality rate of 1.6% for LMAH and 1.8% for LH.
conclusionsMesh application should be considered for LPHR because it reduces recurrences at least in the mid-term. Overall procedure-related complications and mortality seem to not be increased despite of potential mesh-associated complications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.