ArticlePloS one2015
Blood Lead Levels and Cause-Specific Mortality of Inorganic Lead-Exposed Workers in South Korea.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Impact of Occupational Lead Exposure on Lung Cancer Risk in Korean Male Workers: A Retrospective Cohort Study.Cancer research and treatment · 2026Article
- Lead and cancer: a narrative review and risk of bias assessment (2003-2020).Reviews on environmental health · 2026Review
- Prospective Study on the Association Between Blood Heavy Metal Levels and Pulmonary Function in University Students from a Medical College in Shandong Province, China.International journal of general medicine · 2024Article
- Assessment of Cadmium (Cd) and Lead (Pb) Blood Concentration on the Risk of Endometrial Cancer.Biology · 2023Article
- Environmental Exposure to Metals, Parameters of Oxidative Stress in Blood and Prostate Cancer: Results from Two Cohorts.Antioxidants (Basel, Switzerland) · 2022Article
- Lung cancer incidence among workers biologically monitored for occupational exposure to lead: a cohort study.Scandinavian journal of work, environment & health · 2022Article
- Influence of the Levels of Arsenic, Cadmium, Mercury and Lead on Overall Survival in Lung Cancer.Biomolecules · 2021Article
- Blood lead levels and lung cancer mortality: An updated analysis of NHANES II and III.Cancer medicine · 2021Article
- Association between heavy metals and colon cancer: an ecological study based on geographical information systems in North-Eastern Iran.BMC cancer · 2021Article
- Review
- Blood Lead Concentrations and Mortality in Korean Adults: the Korea National Health and Nutrition Examination Survey with Mortality Follow-Up.International journal of environmental research and public health · 2020Article
- The Immunotoxicity of Chronic Exposure to High Levels of Lead: An Ex Vivo Investigation.Toxics · 2020Article
- Blood lead levels in relation to smoking and chronic obstructive pulmonary disease (COPD): a study from Korean National Health and Nutrition Examination Survey (KNHANES).Journal of thoracic disease · 2020Article
- Interpretation of Population Health Metrics: Environmental Lead Exposure as Exemplary Case.Hypertension (Dallas, Tex. : 1979) · 2020Review
- Dentine biomarkers of prenatal and early childhood exposure to manganese, zinc and lead and childhood behavior.Environment international · 2018Article
- Urinary Lead Concentration Is an Independent Predictor of Cancer Mortality in the U.S. General Population.Frontiers in oncology · 2018Article
- Possible changes of New-Generation inflammation markers with occupational lead exposure.Journal of occupational health · 2017Article
- Exome-wide association study identifies genetic polymorphisms of C12orf51, MYL2, and ALDH2 associated with blood lead levels in the general Korean population.Environmental health : a global access science source · 2017Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to identify the association of blood lead level (BLL) with mortality in inorganic lead-exposed workers of South Korea. A cohort was compiled comprising 81,067 inorganic lead exposed workers working between January 1, 2000, and December 31, 2004. This cohort was merged with the Korean National Statistical Office to follow-up for mortality between 2000 and 2008. After adjusting for age and other carcinogenic metal exposure, all-cause mortality (Relative risk [RR] 1.36, 95% confidence interval [CI] 1.03-1.79), digestive disease (RR 3.23, 95% CI 1.33-7.86), and intentional self-harm (RR 2.92, 95% CI 1.07-7.81) were statistically significantly higher in males with BLL >20 μg/dl than of those with BLL ≤10μg/dl. The RR of males with BLL of 10-20 μg/dl was statistically higher than of those with BLL ≤10μg/dl in infection (RR 3.73. 95% CI, 1.06-13.06). The RRs of females with 10-20 μg/dl BLL was statistically significantly greater than those with BLL <10μg/dl in all-cause mortality (RR 1.93, 95% CI 1.16-3.20) and colon and rectal cancer (RR 13.42, 95% CI 1.21-149.4). The RRs of females with BLL 10-20 μg/dl (RR 10.45, 95% CI 1.74-62.93) and BLL ≥20 μg/dl (RR 12.68, 95% CI 1.69-147.86) was statistically significantly increased in bronchus and lung cancer. The increased suicide of males with ≥20 μg/dl BLLs, which might be caused by major depression, might be associated with higher lead exposure. Also, increased bronchus and lung cancer mortality in female workers with higher BLL might be related to lead exposure considering low smoking rate in females. The kinds of BLL-associated mortality differed by gender.
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