Evidence map›Paper›PMID 26468988›Full record

ArticleJournal of child and adolescent psychopharmacology2015

Affective Processing in Pediatric Bipolar Disorder and Offspring of Bipolar Parents.

Isabelle E Bauer, Thomas W Frazier, Thomas D Meyer, Eric Youngstrom, Giovana B Zunta-Soares, Jair C Soares

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of child and adolescent psychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07396363 (The Effect of Psychoeducational Psychotherapy on Neurocognitive Functions, Quality of Life, And Emotion Regulation in Adolescents Diagnosed With Bipolar Disorder), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07396363 nacompletednot on this mapstarted 2017, after this paper: background citation

The Effect of Psychoeducational Psychotherapy on Neurocognitive Functions, Quality of Life, And Emotion Regulation in Adolescents Diagnosed With Bipolar Disorder: A Randomized Controlled Trial

TypeinterventionalSponsorDokuz Eylul UniversityRan2017 to 2022Enrolled32ConditionsBipolar Disorder (BD)ArmsPsychoeducational psychotherapy (PEP)
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Isabelle E Bauer1 Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston , Houston, Texas.
Thomas W Frazier2 Cleveland Clinic, Pediatric Institute , Cleveland, Ohio.
Thomas D Meyer1 Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston , Houston, Texas.
Eric Youngstrom3 Psychology Department, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.
Giovana B Zunta-Soares1 Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston , Houston, Texas.
Jair C Soares1 Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston , Houston, Texas.
The University of Texas Health Science Center at Houston · US

Funding

Fronto-Limbic Brain of Bipolar Children and AdolescentsR01MH069774 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YOUNGSTROM, ERIC · 2005 to 2008
$1.9M
NIMH NIH HHS R01MH69774
6 · The paper itself

Abstract

backgroundBipolar disorder (BD) is characterized by biased processing of emotional information. However, little research in this area has been conducted in youth with BD and at-risk individuals. The goal of this study was to determine whether children with BD displayed comparable or more severe manifestations of this bias relative to offspring of parents with BD. MATERIALS AND

methodsThe sample (n = 57 children and adolescents) included 18 individuals with BD (age: 13.63 ± 2.99; 8 females), 16 offspring of parents with BD (age: 11.83 ± 2.96; 9 females) and 23 healthy controls (HC) (age: 12.789 ± 3.087; 8 females). All participants performed the Affective Go/No-Go (AGN) and the Rapid Visual Processing (RVP) tasks of the Cambridge Neuropsychological Test Automated Battery (CANTAB).

resultsRelative to HC, individuals with BD responded faster to correct trials and committed an elevated number of commission errors across all affective conditions of the AGN task. By contrast, BD offspring showed intact performance accuracy but quicker response times than HC. Post-hoc analyses revealed that this behavioral pattern was observed in BD offspring with mental health problems but not in healthy BD offspring. Overall, mean reaction times and total number of errors in the RVP task were comparable across groups.

conclusionsIn line with previous findings, subjects with BD encountered difficulties in processing affective information. The tendency toward faster but accurate responses to affective stimuli observed in BD offspring may be a marker of attentional bias toward affective information and constitute a vulnerability marker for mood disorder.

Indexed as

EmotionsMental ProcessesAdolescentBipolar DisorderCase-Control StudiesChildChild of Impaired ParentsFemaleHumansMaleNeuropsychological TestsReaction Time

Identifiers

PMID26468988
PMCPMC4653817
OpenAlexW2408950630

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.