Evidence map›Paper›PMID 26468745›Full record

ReviewCell host & microbe2015

Cell-Cycle Regulators and Cell Death in Immunity.

Sophia G Zebell, Xinnian Dong

Open access · bronzeAbstract readComparative StudyReview
In one paragraph

Review in Cell host & microbe, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Wheat AnnexinInternational journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. A novel elicitor protein phosphopentomutase fromFrontiers in plant science · 2022
    Article
  14. Salicylic Acid andFrontiers in plant science · 2022
    Review
  15. Frontiers in immunology · 2022
    Article
  16. Article
  17. Article
  18. Characterization ofFrontiers in microbiology · 2021
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sophia G ZebellDepartment of Biology, Howard Hughes Medical Institute-Gordon and Betty Moore Foundation, P.O. Box 90338, Duke University, Durham, NC 27708, USA.
Xinnian DongDepartment of Biology, Howard Hughes Medical Institute-Gordon and Betty Moore Foundation, P.O. Box 90338, Duke University, Durham, NC 27708, USA. Electronic address: xdong@duke.edu.
Howard Hughes Medical Institute · US

Funding

ORGANIZATION AND FUNCTIONS OF CELLULAR STRUCTUREST32GM007184 · NIGMS · DUKE UNIVERSITY · PI JINKS-ROBERTSON, SUE · 1985 to 2019
$18.2M
Functional Analyses of NPR1 in Plant DefenseR01GM069594 · NIGMS · DUKE UNIVERSITY · PI DONG, XINNIAN · 2004 to 2016
$3.8M
Howard Hughes Medical InstituteHoward Hughes Medical Institute GBMF3032NIGMS NIH HHS 2R01-GM069594-09NIGMS NIH HHS R01 GM069594NIGMS NIH HHS T32 GM007184
6 · The paper itself

Abstract

Various cell death mechanisms are integral to host defense in both plants and mammals. Plant defense against biotrophic pathogens is associated with programmed cell death (PCD) of the infected cell. This effector-triggered PCD is partly analogous to pyroptosis, an inflammatory host cell death process that plays a crucial role in defense against microbial infections in mammals. Plant effector-triggered PCD also shares with mammalian apoptosis the involvement of cell-cycle regulators as signaling components. Here we explore the similarities between these different cell death programs as they relate to host defense and their relationship to the cell cycle.

Indexed as

ApoptosisCell CycleImmunity, InnateAnimalsMammalsPlantsSignal Transduction

Identifiers

PMID26468745
PMCPMC4609028
OpenAlexW1950287089

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.