Evidence map›Paper›PMID 26468444›Full record

ArticleWorld journal of clinical oncology2015

New findings on thymic epithelial tumors: Something is changing.

Rossana Berardi, Francesca Morgese, Marina Chiara Garassino, Stefano Cascinu

Open access · hybridAbstract read
In one paragraph

Article in World journal of clinical oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rossana BerardiRossana Berardi, Francesca Morgese, Stefano Cascinu, Department of Medical Oncology, Università Politecnica Marche, 60126 Ancona, Italy.
Francesca MorgeseRossana Berardi, Francesca Morgese, Stefano Cascinu, Department of Medical Oncology, Università Politecnica Marche, 60126 Ancona, Italy.
Marina Chiara GarassinoRossana Berardi, Francesca Morgese, Stefano Cascinu, Department of Medical Oncology, Università Politecnica Marche, 60126 Ancona, Italy.
Stefano CascinuRossana Berardi, Francesca Morgese, Stefano Cascinu, Department of Medical Oncology, Università Politecnica Marche, 60126 Ancona, Italy.
Marche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thymic epithelial tumors (TETs) are uncommon neoplasms with a wide range of anatomical, clinical, histological and molecular malignant entities. To date the management of TETs within clinical practice is based on a multimodal therapeutic strategy including surgery, chemotherapy and radiotherapy with a multidisciplinary approach and prognostic evaluation is mainly based on Masaoka staging and World Health Organization classification. Therefore novel strategies are needed, especially for refractory and/or recurrent TETs and for thymic carcinomas that present a poor prognosis. Personalized approaches are currely being developed and molecular targets are emerging from recent integrated genomic analyses. Targeted therapy will represent an important treatment option for TETs with an aggressive histology. To date, data indicate that vascular endothelial growth factor molecules, insulin-like growth factor 1 receptor, cyclin-dependent kinases and mammalian target of rapamycin may be potentially useful as targeted biological therapies.

Indexed as

Programmed cell death-1Targeted therapyThymic carcinomaThymic epithelial tumorsThymoma

Identifiers

PMID26468444
PMCPMC4600197
OpenAlexW1849869867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.