ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2015
Disrupted Sleep: From Molecules to Cognition.
Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 46 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Circadian Health in Patients Admitted to Intensive Care Units and Hospitalization (CHRONOHOSPI)
Inter-individual Variability of Sleep Outcome Measures in Response to Nutritional Blend Supplementation: a Replicate Crossover Trial
Who cites it
46 citing papers in PubMed, 125 citations in OpenAlex.
- Sleep disturbances after an ultra-trail endurance race: a field study.Sleep medicine: X · 2026Article
- Sleep Temporal Entropy as a Novel Digital Biomarker of Sleep Fragmentation for Cardiometabolic and Mortality Risk.Research square · 2025Article
- Blood Clock Correlation Distance (BloodCCD) as a novel marker to detect circadian rhythm disruption in cancer survivors with insomnia.BJC reports · 2025Article
- Sleep Temporal Entropy as a Novel Digital Biomarker of Sleep Fragmentation for Cardiometabolic and Mortality Risk.medRxiv : the preprint server for health sciences · 2025Article
- Age-related disturbances in rest-activity rhythms and integrity of the hippocampal network: An exploratory study.Neurobiology of sleep and circadian rhythms · 2025Article
- Actigraphy-assessed sleep duration and quality and executive function in a sample of typically developing preschoolers.European child & adolescent psychiatry · 2025Article
- Underlying biological mechanisms of emotion dysregulation in bipolar disorder.Frontiers in psychiatry · 2025Review
- Enhancing sleep, wakefulness, and cognition with transcranial photobiomodulation: a systematic review.Frontiers in behavioral neuroscience · 2025Review
- Dietary patterns and quality of life among night-shift nurses in tertiary hospitals in Hangzhou: a cross-sectional analysis.Frontiers in public health · 2025Article
- Accelerometer-measured sleep behaviour and parent-child sleep guideline adherence and sleep quality in Czech families with children aged 3-8 years: the FAMIly Physical Activity, Sedentary behaviour and Sleep (FAMIPASS) study.Journal of sleep research · 2024Article
- The Role of Cannabis and The Endocannabinoid System in Sleep Regulation and Cognition: A Review of Human and Animal Studies.Behavioral sleep medicine · 2024Review
- Sleep Patterns in Children With Blindness: A Comparison With Normally Sighted Peers.Investigative ophthalmology & visual science · 2023Article
- A narrative review of the pathophysiology and impacts of insufficient and disrupted sleep.The Canadian veterinary journal = La revue veterinaire canadienne · 2023Review
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- A literature review of sleep problems and neurodevelopment disorders.Frontiers in psychiatry · 2023Review
- Night-shift work and psychiatric treatment. A follow-up study among employees in Denmark.Scandinavian journal of work, environment & health · 2022Article
- Emotional Dysregulation, Anxiety Symptoms and Insomnia in Individuals with Alcohol Use Disorder.International journal of environmental research and public health · 2022Article
- CX3C-chemokine receptor 1 modulates cognitive dysfunction induced by sleep deprivation.Chinese medical journal · 2021Article
- Specific electromagnetic radiation in the wireless signal range increases wakefulness in mice.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 5 countries.
Funding
Abstract
Although the functions of sleep remain to be fully elucidated, it is clear that there are far-reaching effects of its disruption, whether by curtailment for a single night, by a few hours each night over a long period, or by disruption in sleep continuity. Epidemiological and experimental studies of these different forms of sleep disruption show deranged physiology from subcellular levels to complex affective behavior. In keeping with the multifaceted influence of sleep on health and well-being, we illustrate how the duration of sleep, its timing, and continuity can affect cellular ultrastructure, gene expression, metabolic and hormone regulation, mood, and vigilance. Recent brain imaging studies provide some clues on mechanisms underlying the most common cause of disrupted sleep (insomnia). These insights should ultimately result in adequate interventions to prevent and treat sleep disruption because of their high relevance to our most prevalent health problems. SIGNIFICANCE STATEMENT: Disruption of the duration, timing, and continuity of sleep affects cellular ultrastructure, gene expression, appetite regulation, hormone production, vigilance, and reward functions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.