SynthesisEuropean journal of pediatrics2015
Compliance in oxygen saturation targeting in preterm infants: a systematic review.
Synthesis in European journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Automated versus manual control of inspired oxygen to target oxygen saturation in preterm infants: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2018Pooled it
- Performance and safety of the PRICO closed-loop oxygen saturation targeting system in neonates: pragmatic multicentre cross-over study (TarOx Study).BMJ paediatrics open · 2024Trial
- Oxygen Saturation Targeting in the Neonatal Intensive Care Unit.Journal of clinical medicine · 2025Review
- Continuous Application of Closed-Loop FiO2-Control in Extremely Preterm Infants: A Matched Cohort Single-Center Study.Pediatric pulmonology · 2025Article
- Pulse oximetry in pediatric care: Balancing advantages and limitations.World journal of clinical pediatrics · 2024Article
- Development of a Web-Based Oxygenation Dashboard for Preterm Neonates: A Quality Improvement Initiative.Journal of medical systems · 2024Article
- ROP: 80 Years after Its Detection - Where Do We Stand and How Long Will We Continue to Laser?Neonatology · 2024Review
- Evaluation of the impact of oximeter averaging times on automated FiOFrontiers in pediatrics · 2023Article
- The effect of automated oxygen control on clinical outcomes in preterm infants: a pre- and post-implementation cohort study.European journal of pediatrics · 2021Article
- Behavior of nurses and nurse aides toward influenza vaccine: the impact of the perception of occupational working conditions.Human vaccines & immunotherapeutics · 2020Article
- Using intermittent pulse oximetry to guide neonatal oxygen therapy in a low-resource context.Archives of disease in childhood. Fetal and neonatal edition · 2020Article
- Association of nursing overtime, nurse staffing and unit occupancy with medical incidents and outcomes of very preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2018Article
- Improving Neonatal Care with Technology.Frontiers in pediatrics · 2017Article
- Pulse oximeter saturation target limits for preterm infants: a survey among European neonatal intensive care units.European journal of pediatrics · 2017Article
- IGF-1 in retinopathy of prematurity, a CNS neurovascular disease.Early human development · 2016Review
- Pathophysiology of retinopathy of prematurity.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
- IGF-I in the clinics: Use in retinopathy of prematurity.Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research SocietyReview
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During oxygen therapy in preterm infants, targeting oxygen saturation is important for avoiding hypoxaemia and hyperoxaemia, but this can be very difficult and challenging for neonatal nurses. We systematically reviewed the qualitative and quantitative studies investigating the compliance in targeting oxygen saturation in preterm infants and factors that influence this compliance. We searched PubMed, Embase, Web of Science, Cochrane, CINAHL and ScienceDirect from 2000 to January 2015. Sixteen studies were selected, which involved a total of 2935 nurses and 574 infants. The studies varied in methodology, and we have therefore used a narrative account to describe the data. The main finding is that there is a low compliance in oxygen targeting; the upper alarm limits are inappropriately set, and maintaining the saturation (SpO2) below the upper limit presented particular difficulties. Although there is little data available, the studies indicate that training, titration protocols and decreasing workload could improve awareness and compliance. Automated oxygen regulations have been shown to increase the time that SpO2 is within the target range.
conclusionThe compliance in targeting oxygen during oxygen therapy in preterm infants is low, especially in maintaining the SpO2 below the upper limit. WHAT IS KNOWN: • The use of oxygen in preterm infants is vital, but the optimal strategyremains controversial. • Targeting SpO2 during oxygen therapy in preterm infants has beenshown to reduce mortality and morbidity. WHAT IS NEW: • Review of the literature showed that the compliance in targeting SpO2and alarm settings is low. • Creating awareness of risks of oxygen therapy and benefits in targeting,decreasing nurse/patient ratio and automated oxygen therapy couldincrease compliance.
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