ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2016
Serum 25-hydroxyvitamin D concentration and its determinants in the very old: the Newcastle 85+ Study.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Vitamin D and Lung Outcomes in Elderly COVID-19 Patients.Nutrients · 2021Trial
- Risk factors of osteoporosis in elderly inpatients: A cross-sectional single-centre study.Frontiers in aging · 2023Article
- The Association between 25-Hydroxyvitamin D Concentration and Telomere Length in the Very-Old: The Newcastle 85+ Study.Nutrients · 2021Article
- Nutritional Biomarkers and Associated Factors in Community-Dwelling Older Adults: Findings from the SHIELD Study.Nutrients · 2020Article
- Low serum 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalized with COVID-19 are associated with greater disease severity.Clinical endocrinology · 2020Article
- The Association between 25-Hydroxyvitamin D Concentration and Disability Trajectories in Very Old Adults: The Newcastle 85+ Study.Nutrients · 2020Article
- Vitamin D Deficiency and Sarcopenia in Older Persons.Nutrients · 2019Review
- Article
- Higher Vitamin D Levels Are Associated with Better Attentional Functions: Data from the NorCog Register.The journal of nutrition, health & aging · 2019Article
- Socio-economic determinants of vitamin D deficiency in the older Polish population: results from the PolSenior study.Public health nutrition · 2018Article
- Associations of vitamin D status with dietary intakes and physical activity levels among adults from seven European countries: the Food4Me study.European journal of nutrition · 2018Article
- Nutrition in the Very Old.Nutrients · 2018Review
- Vitamin D Level and Activities of Daily Living in Octogenarians: Cross-Sectional Study.Frontiers in endocrinology · 2018Article
- Prevalence and Predictors of Subclinical Micronutrient Deficiency in German Older Adults: Results from the Population-Based KORA-Age Study.Nutrients · 2017Article
- Comparative analysis of nutritional guidelines for vitamin D.Nature reviews. Endocrinology · 2017Review
- Vitamin D Status, Muscle Strength and Physical Performance Decline in Very Old Adults: A Prospective Study.Nutrients · 2017Observational
- The role of vitamin D in maintaining bone health in older people.Therapeutic advances in musculoskeletal disease · 2017Review
- Vitamin D deficiency is associated with functional decline and falls in frail elderly women despite supplementation.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Recommendations for managing cutaneous disorders associated with advancing age.Clinical interventions in aging · 2016Review
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13 authors at 1 institution in 1 country.
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Abstract
summaryData on vitamin D status in very old adults are lacking. The aim of this study was to assess 25-hydroxyvitamin D [25(OH)D] concentrations and its predictors in 775 adults aged 85 years old living in North-East England. Low 25(OH)D was alarmingly high during winter/spring months, but its biological significance is unknown.
introductionDespite recent concerns about the high prevalence of vitamin D deficiency in much of the British adult and paediatric population, there is a dearth of data on vitamin D status and its predictors in very old adults. The objective of the present study was to describe vitamin D status and its associated factors in a broadly representative sample of very old men and women aged 85 years living in the North East of England (55° N).
methodsSerum concentrations of 25-hydroxyvitamin D [25(OH)D] were analysed in 775 participants in the baseline phase of the Newcastle 85+ cohort study. Season of blood sampling, dietary, health, lifestyle and anthropometric data were collected and included as potential predictors of vitamin D status in ordinal regression models.
resultsMedian serum 25(OH)D concentrations were 27, 45, 43 and 33 nmol/L during spring, summer, autumn and winter, respectively. The prevalence of vitamin D deficiency according to North American Institute of Medicine guidelines [serum 25(OH)D <30 nmol/L] varied significantly with season with the highest prevalence observed in spring (51%) and the lowest prevalence observed in autumn (23%; P < 0.001). Reported median (inter-quartile range) dietary intakes of vitamin D were very low at 2.9 (1.2-3.3) μg/day. In multivariate ordinal regression models, non-users of either prescribed or non-prescribed vitamin D preparations and winter and spring blood sampling were associated with lower 25(OH)D concentrations. Dietary vitamin D intake, disability score and disease count were not independently associated with vitamin D status in the cohort.
conclusionThere is an alarming high prevalence of vitamin D deficiency (<30 nmol/L) in 85-year-olds living in North East England at all times of the year but particularly during winter and spring. Use of vitamin D containing preparations (both supplements and medications) appeared to be the strongest predictor of 25(OH)D concentrations in these very old adults.
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