ArticleBMC veterinary research2015
Functional and diffusion tensor magnetic resonance imaging of the sheep brain.
Article in BMC veterinary research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Brain asymmetry and morphometric measurements of the encephalon in Van cats by magnetic resonance imaging.Open veterinary journal · 2025Article
- Sheep (Ovis aries) training protocol for voluntary awake and unrestrained structural brain MRI acquisitions.Behavior research methods · 2024Article
- Beyond the surface: howFrontiers in neuroscience · 2024Review
- Diffusion tensor imaging tractography in the one-humped camel (Frontiers in veterinary science · 2023Article
- The Sheep as a Large Animal Model for the Investigation and Treatment of Human Disorders.Biology · 2022Review
- Morphometric study of the ventricular indexes in healthy ovine BRAIN using MRI.BMC veterinary research · 2022Article
- Mapping sheep to human brain: The need for a sheep brain atlas.Frontiers in veterinary science · 2022Review
- Transcranial focused ultrasound modulates cortical and thalamic motor activity in awake sheep.Scientific reports · 2021Article
- Diffusion Tensor Imaging Tractography of White Matter Tracts in the Equine Brain.Frontiers in veterinary science · 2020Article
- The development of brain magnetic resonance approaches in large animal models for preclinical research.Animal frontiers : the review magazine of animal agriculture · 2019Article
- Mapping BOLD Activation by Pharmacologically Evoked Tremor in Swine.Frontiers in neuroscience · 2019Article
- Article
- Effects of sonication parameters on transcranial focused ultrasound brain stimulation in an ovine model.PloS one · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundAn ovine model can cast great insight in translational neuroscientific research due to its large brain volume and distinct regional neuroanatomical structures. The present study examined the applicability of brain functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) to sheep using a clinical MR scanner (3 tesla) with a head coil. The blood-oxygenation-level-dependent (BOLD) fMRI was performed on anesthetized sheep during the block-based presentation of external tactile and visual stimuli using gradient echo-planar-imaging (EPI) sequence.
resultsThe individual as well as group-based data processing subsequently showed activation in the eloquent sensorimotor and visual areas. DTI was acquired using 26 differential magnetic gradient directions to derive directional fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values from the brain. White matter tractography was also applied to reveal the macrostructure of the corticospinal tracts and optic radiations.
conclusionsUtilization of fMRI and DTI along with anatomical MRI in the sheep brain could shed light on a broader use of an ovine model in the field of translational neuroscientific research targeting the brain.
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