Evidence map›Paper›PMID 26467764›Full record

Trial reportBMC psychiatry2015

Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial.

Tim Carter, Boliang Guo, David Turner, Ioannis Morres, Elizabeth Khalil, Emily Brighton, Marie Armstrong, Patrick Callaghan

2 registry-linked trialsAbstract readPragmatic Clinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 43 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01474837 nacompletednot on this map

The H.E.A.L.T.H. Project: Help Enabling Active Lifestyles Toward Health in Young People With Depression.

TypeinterventionalSponsorUniversity of NottinghamRan2011Enrolled86ConditionsDepressionArmsIntervention: Exercise and motivational interviewing
NCT06350877 naunknown statusnot on this mapstarted 2024, after this paper: background citation

One-on-one and Group-based Physical Activity Intervention Compared to a Wait-list Control for Post-secondary Student Mental Health and Well-being: A 3-arm Parallel Randomized Controlled Trial

TypeinterventionalSponsorUniversity of TorontoRan2024 to 2025Enrolled93ConditionsPhysical Activity, Mental Health IssueArmsPhysical Activity Intervention
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 13 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tim CarterSchool of Health Sciences, University of Nottingham, Nottingham, UK. Timothy.carter@nottingham.ac.uk.
Boliang GuoDivision of Psychiatry & Applied Psychology, University of Nottingham, Nottingham, UK. boliang.guo@nottingham.ac.uk.
David TurnerSchool of Medicine, University of East Anglia, East Anglia, UK. David.A.Turner@uea.ac.uk.
Ioannis MorresDepartment of Physical Education & Sport Science, University of Thessaly, Trikala, Greece. iomorres@pe.uth.gr.
Elizabeth KhalilSchool of Health Sciences, University of Nottingham, Nottingham, UK. Elizabeth.khalil@nottingham.ac.uk.
Emily BrightonSchool of Health Sciences, University of Nottingham, Nottingham, UK. emilybrighton@hotmail.co.uk.
Marie ArmstrongSpecialist CAMHS, Nottinghamshire Healthcare NHS Trust, Nottingham, UK. Marie.armstrong@nottingham.ac.uk.
Patrick CallaghanSchool of Health Sciences, University of Nottingham, Nottingham, UK. Patrick.callaghan@nottingham.ac.uk.

Funding

Department of Health PB-PG-1208-18097
6 · The paper itself

Abstract

backgroundExercise has been shown to be effective in treating depression, but trials testing the effect of exercise for depressed adolescents utilising mental health services are rare. The aim of this study was to determine the effectiveness of a preferred intensity exercise intervention on the depressive symptoms of adolescents with depression.

methodsWe randomly assigned 87 adolescents who were receiving treatment for depression to either 12 sessions of aerobic exercise at preferred intensity alongside treatment as usual or treatment as usual only. The primary outcome was depressive symptom change using the Children's Depression Inventory 2(nd) Version (CDI-2) at post intervention. Secondary outcomes were health-related quality of life and physical activity rates. Outcomes were taken at baseline, post intervention and at six month follow up.

resultsCDI-2 score reduction did not differ significantly between groups at post-intervention (est. 95% CI -6.82, 1.68, p = 0.23). However, there was a difference in CDI-2 score reduction at six month follow-up in favour of the intervention of -4.81 (est. 95% CI -9.49, -0.12, p = 0.03). Health-related quality of life and physical activity rates did not differ significantly between groups at post-intervention and follow-up.

conclusionsThere was no additional effect of preferred intensity exercise alongside treatment as usual on depressive reduction immediately post intervention. However, effects were observed at six months post-intervention, suggesting a delayed response. However, further trials, with larger samples are required to determine the validity of this finding.

trial registrationClinicalTrials.gov NCT01474837, March 16 2011.

Indexed as

AdolescentDepressionExercise TherapyFemaleHumansMaleMental Health ServicesOutcome Assessment, Health CareQuality of Life

Identifiers

PMID26467764
PMCPMC4605143

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.