Evidence map›Paper›PMID 26467494›Full record

SynthesisHypertension research : official journal of the Japanese Society of Hypertension2016

Isometric exercise training for blood pressure management: a systematic review and meta-analysis to optimize benefit.

Jodie D Inder, Deborah J Carlson, Gudrun Dieberg, James R McFarlane, Nicole Cl Hess, Neil A Smart

3 registry-linked trialsOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Hypertension research : official journal of the Japanese Society of Hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 119 papers, 23 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 23 pooled it
39.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02844296 nacompletednot on this map

Efficacy of a Short-bout Handgrip Exercise Intervention for Smoking Cessation: a Pilot Randomized Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2016 to 2018Enrolled208ConditionsSmoking CessationArmsVideo about exercise, App about exercise, Leaflet about exercise, Video about diet, App about diet
NCT03216317 nacompletednot on this mapstarted 2017, after this paper: background citation

Effect of Handgrip's Isometric Training on Blood Pressure and on the Autonomic Modulation of Hypertense Individuals at the Basic Health Units: A Multicentric Study

TypeinterventionalSponsorHospital Israelita Albert EinsteinRan2017 to 2018Enrolled65ConditionsHypertensionArmsIntervention Group
NCT07513025 narecruitingnot on this mapstarted 2026, after this paper: background citation

The Clinical Effectiveness of Progressive Resistance Training With Elastic Band in Postponing and Preventing Sarcopenia Among Older Adults in Rural Long-Term Care Facilities

TypeinterventionalSponsorCishan Hospital, Ministry of Health and WelfareRan2026 to 2026Enrolled60ConditionsSarcopenia, Long Term Care FacilityArmselastic band
3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 23 syntheses or guidelines pooled it, 248 citations in OpenAlex.

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  10. Effectiveness of Physical Activity and Exercise on Ambulatory Blood Pressure in Adults with Resistant Hypertension: A Systematic Review and Meta-Analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022
    Pooled it
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  15. Guideline
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  20. The 2017 Dutch Physical Activity Guidelines.The international journal of behavioral nutrition and physical activity · 2018
    Pooled it

59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jodie D InderSchool of Science and Technology, University of New England, Armidale, New South Wales, Australia.
Deborah J CarlsonSchool of Science and Technology, University of New England, Armidale, New South Wales, Australia.
Gudrun DiebergSchool of Science and Technology, University of New England, Armidale, New South Wales, Australia.
James R McFarlaneSchool of Science and Technology, University of New England, Armidale, New South Wales, Australia.
Nicole Cl HessSchool of Science and Technology, University of New England, Armidale, New South Wales, Australia.
Neil A SmartSchool of Science and Technology, University of New England, Armidale, New South Wales, Australia.
University of New England · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of our study was to examine the effects of isometric resistance training (IRT) on resting blood pressure in adults. We conducted a systematic review and meta-analysis of randomized-controlled trials lasting ⩾2 weeks, investigating the effects of isometric exercise on blood pressure in healthy adults (aged ⩾18 years), published in a peer-reviewed journal between 1 January 1966 to 31 January 2015. We included 11 randomized trials, totaling 302 participants. The following reductions were observed after isometric exercise training; systolic blood pressure (SBP) mean difference (MD) -5.20 mm Hg (95% confidence interval (CI) -6.08 to -4.33, P<0.00001); diastolic blood pressure (DBP) MD -3.91 mm Hg (95% CI -5.68 to -2.14, P<0.0001); and mean arterial blood pressure (MAP) MD -3.33 mm Hg (95% CI -4.01 to -2.66, P<0.00001). Sub-analyses showed males tended to reduce MAP MD -4.13 mm Hg (95% CI -5.08 to -3.18) more than females. Subjects aged ⩾45 years demonstrated larger reductions in MAP MD -5.51 mm Hg (95% CI -6.95 to -4.06) than those <45 years. Subjects undertaking ⩾8 weeks of IRT demonstrated a larger reduction in SBP MD -7.26 mm Hg (95% CI -8.47 to -6.04) and MAP MD -4.22 mm Hg (95% CI -5.08 to -3.37) than those undertaking<8 weeks. Hypertensive participants in IRT demonstrated a larger reduction in MAP MD -5.91 mm Hg (95% CI -7.94 to -3.87) than normotensive participants MD -3.01 mm Hg (95% CI -3.73 to -2.29). Our study indicated that IRT lowers SBP, DBP and MAP. The magnitude of effect may be larger in hypertensive males aged ⩾45 years, using unilateral arm IRT for >8 weeks.

Indexed as

Blood PressureAdultAgedExerciseFemaleHumansHypertensionMaleMiddle AgedPhysical Education and TrainingSex Characteristics

Identifiers

PMID26467494
OpenAlexW2261873586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.