ArticleAnatolian journal of cardiology2016
Femoral neck and spine bone mineral density-Surrogate marker of aortic calcification in postmenopausal women.
Article in Anatolian journal of cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- Smoking shapes the relationship between metabolic biomarkers and femoral-neck bone mineral density: A stratified analysis by smoking status.Tobacco induced diseases · 2026Article
- Automated quantification of abdominal aortic calcification using 3D nnU-Net: a novel approach to assess AAA rupture risk.BMC medical imaging · 2025Article
- Value of quantitative ultrasound and bioelectrical impedance analysis in detecting low bone mineral density in hemodialysis.Renal failure · 2021Article
- No Association Between Bone Mineral Density and Breast Arterial Calcification Among Postmenopausal Women.Journal of the Endocrine Society · 2020Article
- Bone Strength and Arterial Stiffness Impact on Cardiovascular Mortality in a General Population.Journal of osteoporosis · 2016Article
- Aortic Calcification Artifact Causing Spuriously High Bone Mineral Density in the Lumbar Spine.AACE clinical case reportsArticle
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Authors and funding
4 authors at 1 institution in 1 country.
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Abstract
objectiveOsteoporosis and abdominal aortic calcification (AAC) are associated with increased morbidity and mortality in postmenopausal women. The aim of this study was to determine the accuracy of anterior-posterior (AP) dual-energy X-ray absorptiometry (DXA) compared with that of X-ray lateral lumbar radiography (LLR) in detecting and scoring AAC.
methodsIn this cross-sectional study conducted in 56 postmenopausal asymptomatic females aged 59.0 ± 9.3 years and who never used medications to treat osteoporosis before, we determined femoral neck and lumbar spine bone mineral density (BMD) by AP DXA and AAC by X-ray LLR. We hypothesized that the subtracted femoral neck BMD (BMDFN) from lumbar spine BMD (BMDLS) presented as ΔBMD=BMDLS-BMDFN would have a diagnostic value in detecting abdominal vascular calcification.
resultsThe mean BMDFN was 0.744 ± 0.184 g/cm(2), and the mean BMDLS was 0.833 ± 0.157 g/cm(2) (p<0.0001); the mean ΔBMD was 0.089 ± 0.077 g/cm(2), and the mean AAC score was 2.182 ± 1.982. Bivariate Pearson's correlation analysis revealed a significant positive correlation between AAC and ΔBMD (r=0.449, p=0.0006); by linear regression analysis, R(2)=0.2019, and by multiple regression analysis, βst=13.5244 (p<0.0001). We found a sensitivity of 64.3% and specificity of 82.9% by receiver operating characteristic [ROC; area under the ROC curve (AUC=0.759)] in the prediction of AAC by ΔBMD.
conclusionThis AP subtracting BMD DXA method provides a useful tool for detecting and scoring subclinical and extensive AAC in postmenopausal women using a simple, semiquantitative, and accurate scoring system with minimal radiation exposure and low cost.
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