Evidence map›Paper›PMID 26467327›Full record

Trial reportJournal of traumatic stress2015

Technology-Enhanced Stepped Collaborative Care Targeting Posttraumatic Stress Disorder and Comorbidity After Injury: A Randomized Controlled Trial.

Douglas Zatzick, Stephen S O'Connor, Joan Russo, Jin Wang, Nigel Bush, Jeff Love, Roselyn Peterson, Leah Ingraham, Doyanne Darnell, Lauren Whiteside and 1 more

Registry-linked trialAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Journal of traumatic stress, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01625416 (Integrating Information Technology Advancements Into Early PTSD Interventions), which is not on this map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01625416 nacompletednot on this map

Integrating Information Technology Advancements Into Early PTSD Interventions

TypeinterventionalSponsorUniversity of WashingtonRan2012 to 2015Enrolled121ConditionsPosttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain InjuryArmsStepped Care Management
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  12. Optimizing acute pain management in trauma care: the role, structure and core principles of acute trauma pain services.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Douglas ZatzickDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Stephen S O'ConnorDepartment of Psychological Sciences, Western Kentucky University, Bowling Green, Kentucky, USA.
Joan RussoDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Jin WangDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Nigel BushDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Jeff LoveDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Roselyn PetersonDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Leah IngrahamDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Doyanne DarnellDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Lauren WhitesideDepartment of Emergency Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
Erik Van EatonDepartment of Surgery, University of Washington School of Medicine, Seattle, Washington, USA.

Funding

A longitudinal collaborative care model for patients with prescription opioid misuse utilizing the Emergency Department for careK23DA039974 · NIDA · UNIVERSITY OF WASHINGTON · PI WHITESIDE, LAUREN K · 2015 to 2019
$906k
Research, Mentoring & Dissemination for PTSD Intervention in Acute Care SettingsK24MH086814 · NIMH · UNIVERSITY OF WASHINGTON · PI ZATZICK, DOUGLAS F · 2010 to 2014
$867k
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and ComorbidityUH2MH106338 · NIMH · UNIVERSITY OF WASHINGTON · PI ZATZICK, DOUGLAS F · 2014 to 2014
$782k
NIDA NIH HHS K23 DA039974NIMH NIH HHS 1UH2MH106338NIMH NIH HHS K24 MH086814NIMH NIH HHS K24MH086814NIMH NIH HHS UH2 MH106338
6 · The paper itself

Abstract

Posttraumatic stress disorder (PTSD) and its comorbidities are endemic among injured trauma survivors. Previous collaborative care trials targeting PTSD after injury have been effective, but they have required intensive clinical resources. The present pragmatic clinical trial randomized acutely injured trauma survivors who screened positive on an automated electronic medical record PTSD assessment to collaborative care intervention (n = 60) and usual care control (n = 61) conditions. The stepped measurement-based intervention included care management, psychopharmacology, and psychotherapy elements. Embedded within the intervention were a series of information technology (IT) components. PTSD symptoms were assessed with the PTSD Checklist at baseline prerandomization and again, 1-, 3-, and 6-months postinjury. IT utilization was also assessed. The technology-assisted intervention required a median of 2.25 hours (interquartile range = 1.57 hours) per patient. The intervention was associated with modest symptom reductions, but beyond the margin of statistical significance in the unadjusted model: F(2, 204) = 2.95, p = .055. The covariate adjusted regression was significant: F(2, 204) = 3.06, p = .049. The PTSD intervention effect was greatest at the 3-month (Cohen's effect size d = 0.35, F(1, 204) = 4.11, p = .044) and 6-month (d = 0.38, F(1, 204) = 4.10, p = .044) time points. IT-enhanced collaborative care was associated with modest PTSD symptom reductions and reduced delivery times; the intervention model could potentially facilitate efficient PTSD treatment after injury.

Indexed as

AdultAntidepressive AgentsCognitive Behavioral TherapyComorbidityCooperative BehaviorDecision Support Systems, ClinicalDelivery of Health Care, IntegratedFemaleHumansMaleMotivational InterviewingOutcome and Process Assessment, Health CareRisk AssessmentRisk-TakingStress Disorders, Post-TraumaticUnited StatesAntidepressive Agents

Identifiers

PMID26467327
PMCPMC5549940

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.