Evidence map›Paper›PMID 26467033›Full record

ArticleUrolithiasis2016

Clinical, demographic, and laboratory characteristics of children with nephrolithiasis.

David J Sas, Lauren J Becton, Jeffrey Tutman, Laura A Lindsay, Amy H Wahlquist

Abstract read
In one paragraph

Article in Urolithiasis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Risk factors for recurrence in pediatric urinary stone disease.Pediatric nephrology (Berlin, Germany) · 2024
    Article
  7. Epidemiology of Kidney Stones.Healthcare (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Nephrolithiasis: Approach to Diagnosis and Management.Indian journal of pediatrics · 2020
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. CLINICAL-EPIDEMIOLOGICAL PROFILE OF 106 PEDIATRIC PACIENTS WITH UROLITHIASIS IN RIO DE JANEIRO, BRAZIL.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David J SasDivision of Pediatric Nephrology and Hypertension, Department of Pediatric and Adolescent Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. sas.david@mayo.edu.
Lauren J BectonDivision of Pediatric Nephrology, Department of Pediatrics, Albert Einstein School of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.
Jeffrey TutmanUniversity of Utah Department of Radiology, 30 North 1900 East #1A071, Salt Lake City, UT, 84132, USA.
Laura A LindsayChildren's Emergency Services, Dayton Children's Hospital, 1 Children's Plaza, Dayton, OH, 45404, USA.
Amy H WahlquistDivision of Biostatistics and Epidemiology, Department of Medicine, Medical University of South Carolina, 96 Jonathan Lucas St., Suite 803 MSC 623, Charleston, SC, 29425, USA.

Funding

SOUTH CAROLINA CLINICAL & TRANSLATIONAL RESEARCH INSTITUTE (SCTR)UL1RR029882 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2009 to 2011
$10.1M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR000062 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2012 to 2014
$9.4M
NCATS NIH HHS UL1 TR000062NCRR NIH HHS UL1 RR029882
6 · The paper itself

Abstract

While the incidence of pediatric kidney stones appears to be increasing, little is known about the demographic, clinical, laboratory, imaging, and management variables in this patient population. We sought to describe various characteristics of our stone-forming pediatric population. To that end, we retrospectively reviewed the charts of pediatric patients with nephrolithiasis confirmed by imaging. Data were collected on multiple variables from each patient and analyzed for trends. For body mass index (BMI) controls, data from the general pediatrics population similar to our nephrolithiasis population were used. Data on 155 pediatric nephrolithiasis patients were analyzed. Of the 54 calculi available for analysis, 98 % were calcium based. Low urine volume, elevated supersaturation of calcium phosphate, elevated supersaturation of calcium oxalate, and hypercalciuria were the most commonly identified abnormalities on analysis of 24-h urine collections. Our stone-forming population did not have a higher BMI than our general pediatrics population, making it unlikely that obesity is a risk factor for nephrolithiasis in children. More girls presented with their first stone during adolescence, suggesting a role for reproductive hormones contributing to stone risk, while boys tended to present more commonly at a younger age, though this did not reach statistical significance. These intriguing findings warrant further investigation.

Indexed as

AdolescentChildChild, PreschoolDemographyFemaleHumansMaleNephrolithiasisObesityRetrospective StudiesYoung AdultAdolescentsKidney stonesNephrolithiasisObesityPediatricsUrolithiasis

Identifiers

PMID26467033
PMCPMC5215772

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.