Evidence map›Paper›PMID 26466845›Full record

ArticleActa ophthalmologica2016

The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population.

Catherine Creuzot-Garcher, Christine Binquet, Sandrine Daniel, Lionel Bretillon, Nyiazi Acar, Aurélie de Lazzer, Laurent Arnould, Christophe Tzourio, Alain M Bron, Cécile Delcourt

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Acta ophthalmologica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Catherine Creuzot-GarcherDepartment of Ophthalmology, University Hospital, Dijon, France.
Christine BinquetDepartment of Epidemiology, University Hospital, Dijon, France.
Sandrine DanielDepartment of Epidemiology, University Hospital, Dijon, France.
Lionel BretillonINRA, UMR1324 Center for Taste and Feeding Behavior, Dijon, France.
Nyiazi AcarINRA, UMR1324 Center for Taste and Feeding Behavior, Dijon, France.
Aurélie de LazzerDepartment of Ophthalmology, University Hospital, Dijon, France.
Laurent ArnouldDepartment of Ophthalmology, University Hospital, Dijon, France.
Christophe TzourioINSERM, Centre INSERM U897, Univ Bordeaux, ISPED, Bordeaux, France.
Alain M BronDepartment of Ophthalmology, University Hospital, Dijon, France.
Cécile DelcourtINSERM, Centre INSERM U897, Univ Bordeaux, ISPED, Bordeaux, France.
Maison des Sciences de l’Homme de Dijon · FRUniversité de Bourgogne · FRBordeaux Population Health · FRCentre National de la Recherche Scientifique · FRInserm · FRLaboratoire d'étude de l'apprentissage et du développement · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the design of the Montrachet Study (Maculopathy Optic Nerve nuTRition neurovAsCular and HEarT diseases) and to report visual acuity and refractive errors in this elderly population.

methodsParticipants were recruited in Dijon (France), from the ongoing population-based 3C Study. In 2009-2011, 1153 participants from the 3 Cities Study, aged 75 years or more, had an initial eye examination and were scheduled for eye examinations. The eye examination comprised visual acuity, refraction, visual field, ocular surface assessment, photographs and OCT of the macula and the optic disc, measurement of intra-ocular pressure, central corneal thickness and macular pigment assessment. Information on cardiovascular and neurologic diseases and a large comprehensive database (blood samples, genetic testing, cognitive tests, MRI) were available from the 3C Study.

resultsPresenting visual acuity <20/60 in the better eye was found in 2.3% (95% CI 1.5-3.2) of the participants with no gender differences. Visual impairment increased with age from 1.5% (95% CI 0.3-2.7) for those aged 75-79 years to 5.6% (95% CI 2.9-8.4) for patients 85 years and older (p = 0.0003). Spherical equivalent did not differ between men and women (p = 0.8) and decreased with age whatever the lens status.

conclusionDespite the high prevalence of self-reported eye diseases in this elderly population, visual impairment was low and increased with age. The Montrachet Study may help to better estimate the prevalence of eye diseases in people over 75 years of age and to seek associations with cardiovascular and neurologic diseases and their potential risk factors.

Indexed as

AgingAgedAged, 80 and overCardiovascular DiseasesCorneal PachymetryData CollectionFemaleFranceHumansMacular PigmentMaleNervous System DiseasesPersons with Visual DisabilitiesPrevalenceRefractive ErrorsResearch DesignMacular Pigmentcardiovascular diseaseselderlyeye diseasesneurologic diseasesnutritionpopulation-based study

Identifiers

PMID26466845
PMCPMC5057364
OpenAlexW1904151506

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.