ReviewInsects2012
General Stress Responses in the Honey Bee.
Review in Insects, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed.
- Exploring emotional expression in invertebrates: mechanisms, functions and phylogeny.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- Role of dopamine signaling in male courtship suppression induced by confinement stress iniScience · 2026Article
- Article
- Article
- Fungal extracts influence lifespan and immune responses in the Carniolan honey bee (Apis mellifera carnica, Pollmann 1879).Scientific reports · 2026Article
- Neurotranscriptomic profiling of deformed wing virus-infected honey bee foragers (Apis mellifera) with different cognitive abilities.Biology open · 2025Article
- Leveraging Transcriptional Signatures of Diverse Stressors for Bumble Bee Conservation.Molecular ecology · 2025Article
- Climate change-induced stress in the honey beeFrontiers in physiology · 2025Review
- Exposure to constant artificial light alters honey bee sleep rhythms and disrupts sleep.Scientific reports · 2024Article
- Based proteomics analyses reveal response mechanisms of Apis mellifera (Hymenoptera: Apidae) against the heat stress.Journal of insect science (Online) · 2024Article
- Antioxidant activities of Saudi honey samples related to their content of short peptides.Scientific reports · 2024Article
- Changes in Selected Biochemical Markers of Honey Bees Exposed to Fermented Common Tansy Solution (Animals : an open access journal from MDPI · 2024Article
- Physically stressed bees expect less reward in an active choice judgement bias test.Proceedings. Biological sciences · 2024Article
- Impact of copper and zinc oral chronic exposure on Carniolan honey bee survival and feeding preference.Journal of economic entomology · 2024Article
- Effects of agricultural landscape structure and canola coverage on biochemical and physiological traits of the ground beetle Poecilus cupreus.Ecotoxicology (London, England) · 2023Article
- Low Levels of Hive Stress Are Associated with Decreased Honey Activity and Changes to the Gut Microbiome of Resident Honey Bees.Microbiology spectrum · 2023Article
- Behavioural Indicators of Pain and Suffering in Arthropods and Might Pain Bite Back?Animals : an open access journal from MDPI · 2023Review
- Using physiology to better support wild bee conservation.Conservation physiology · 2023Article
- Overlapping exposure effects of pathogen and dimethoate on honeybee (Frontiers in physiology · 2023Article
- Identification of runs of homozygosity in Western honey bees (Ecology and evolution · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The biological concept of stress originated in mammals, where a "General Adaptation Syndrome" describes a set of common integrated physiological responses to diverse noxious agents. Physiological mechanisms of stress in mammals have been extensively investigated through diverse behavioral and physiological studies. One of the main elements of the stress response pathway is the endocrine hypothalamo-pituitary-adrenal (HPA) axis, which underlies the "fight-or-flight" response via a hormonal cascade of catecholamines and corticoid hormones. Physiological responses to stress have been studied more recently in insects: they involve biogenic amines (octopamine, dopamine), neuropeptides (allatostatin, corazonin) and metabolic hormones (adipokinetic hormone, diuretic hormone). Here, we review elements of the physiological stress response that are or may be specific to honey bees, given the economical and ecological impact of this species. This review proposes a hypothetical integrated honey bee stress pathway somewhat analogous to the mammalian HPA, involving the brain and, particularly, the neurohemal organ corpora cardiaca and peripheral targets, including energy storage organs (fat body and crop). We discuss how this system can organize rapid coordinated changes in metabolic activity and arousal, in response to adverse environmental stimuli. We highlight physiological elements of the general stress responses that are specific to honey bees, and the areas in which we lack information to stimulate more research into how this fascinating and vital insect responds to stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.