ArticleJournal of experimental botany2016
Dormancy-associated MADS-box genes and microRNAs jointly control dormancy transition in pear (Pyrus pyrifolia white pear group) flower bud.
Article in Journal of experimental botany, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.
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Who cites it
106 citing papers in PubMed.
- PpERF27-PpCBF2/4 Module Integrates Low-Temperature and Ethylene Signals to Activate Abscisic Acid and DAM Pathways to Promote Bud Endodormancy in Peach.Plant, cell & environment · 2026Article
- Uncovering novel loci and developing functional Kompetitive Allele Specific PCR markers for chilling requirement in peach via genome-wide association study.Horticulture research · 2026Article
- From chill to bloom: seasonal coordination of reproductive development in peach and temperate fruit trees.Journal of experimental botany · 2026Review
- PsGA2ox2 is a novel target of miR159 involved in endodormancy regulation in tree peony (Paeonia suffruticosa).Molecular horticulture · 2026Article
- Genome-Wide Analysis of the MADS-Box Gene Family and Expression Pattern Under Abiotic Stresses inInternational journal of molecular sciences · 2026Article
- Comprehensive analysis of DOF transcription factors and characterization of PlOBP4 during herbaceous peony bud dormancy.Plant cell reports · 2026Article
- PacBio full-length transcriptome and WGCNA reveal varietal co-expression networks and regulatory dynamics during tea plant (Frontiers in plant science · 2026Article
- Integrated Multi-Omics Reveals DAM-Mediated Phytohormone Regulatory Networks Driving Bud Dormancy in 'Mixue' Pears.Plants (Basel, Switzerland) · 2025Article
- Article
- Artificial Sweet Cherry miRNA 396 Promotes Early Flowering in Vernalization-Dependent Arabidopsis Edi-0 Ecotype.Plants (Basel, Switzerland) · 2025Article
- Analysis of metabolites change from reflorescence buds of 'Cuiguan' pear (Frontiers in plant science · 2025Article
- Seed coat-derived ABA regulates seed dormancy ofFrontiers in plant science · 2025Article
- Deciphering the genetic mechanisms of chilling requirement for bud endodormancy release in deciduous fruit trees.Molecular breeding : new strategies in plant improvement · 2024Article
- Dormancy regulator Prunus mume DAM6 promotes ethylene-mediated leaf senescence and abscission.Plant molecular biology · 2024Article
- The Complex FtBBX22 and FtHY5 Positively Regulates Light-Induced Anthocyanin Accumulation by ActivatingInternational journal of molecular sciences · 2024Article
- MIKC type MADS-box transcription factor LcSVP2 is involved in dormancy regulation of the terminal buds in evergreen perennial litchi (Horticulture research · 2024Article
- Key transcription factors regulate fruit ripening and metabolite accumulation in tomato.Plant physiology · 2024Article
- Molecular Mechanisms of Seasonal Gene Expression in Trees.International journal of molecular sciences · 2024Review
- Integrated metabolome and transcriptome analysis reveals potential mechanism during the bud dormancy transition ofFrontiers in plant science · 2024Article
- Genetic and molecular regulation of chilling requirements in pear: breeding for climate change resilience.Frontiers in plant science · 2024Review
46 more citing papers are in PubMed but not listed here.
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10 authors.
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Abstract
Bud dormancy in perennial plants is indispensable to survival over winter and to regrowth and development in the following year. However, the molecular pathways of endo-dormancy induction, maintenance, and release are still unclear, especially in fruit crops. To identify genes with roles in regulating endo-dormancy, 30 MIKC(C)-type MADS-box genes were identified in the pear genome and characterized. The 30 genes were analysed to determine their phylogenetic relationships with homologous genes, genome locations, gene structure, tissue-specific transcript profiles, and transcriptional patterns during flower bud dormancy in 'Suli' pear (Pyrus pyrifolia white pear group). The roles in regulating bud dormancy varied among the MIKC gene family members. Yeast one-hybrid and transient assays showed that PpCBF enhanced PpDAM1 and PpDAM3 transcriptional activity during the induction of dormancy, probably by binding to the C-repeat/DRE binding site, while DAM proteins inhibited the transcriptional activity of PpFT2 during dormancy release. In the small RNA-seq analysis, 185 conserved, 24 less-conserved, and 32 pear-specific miRNAs with distinct expression patterns during bud dormancy were identified. Joint analyses of miRNAs and MIKC genes together with degradome data showed that miR6390 targeted PpDAM transcripts and degraded them to release PpFT2. Our data show that cross-talk among PpCBF, PpDAM, PpFT2, and miR6390 played important roles in regulating endo-dormancy. A model for the molecular mechanism of dormancy transition is proposed: short-term chilling in autumn activates the accumulation of CBF, which directly promotes DAM expression; DAM subsequently inhibits FT expression to induce endo-dormancy, and miR6390 degrades DAM genes to release endo-dormancy.
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