Evidence map›Paper›PMID 26466315›Full record

ArticlePloS one2015

Prepregnancy Obesity and Risks of Stillbirth.

Suzan L Carmichael, Yair J Blumenfeld, Jonathan Mayo, Emily Wei, Jeffrey B Gould, David K Stevenson, Gary M Shaw, March of Dimes Prematurity Research Center at Stanford University School of Medicine

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Hispanic Ethnicity, Nativity and the Risk of Stillbirth.Journal of immigrant and minority health · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. The Risks Associated With Obesity in Pregnancy.Deutsches Arzteblatt international · 2018
    Review
  10. Obesity in Pregnancy: Optimizing Outcomes for Mom and Baby.The Medical clinics of North America · 2018
    Review
  11. 'The obesity paradox': a reconsideration of obesity and the risk of preterm birth.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Article
  12. Article
  13. Article
  14. Perspectives in obesity and pregnancy.Women's health (London, England) · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Suzan L CarmichaelDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America.
Yair J BlumenfeldDepartment of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California, United States of America.
Jonathan MayoDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America.
Emily WeiDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America.
Jeffrey B GouldDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America.
David K StevensonDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America.
Gary M ShawDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America.
March of Dimes Prematurity Research Center at Stanford University School of Medicine
Stanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe examined the association of maternal obesity with risk of stillbirth, focusing on whether the pattern of results varied by gestational age or maternal race-ethnicity or parity.

methodsAnalyses included 4,012 stillbirths and 1,121,234 liveborn infants delivered in California from 2007-2010. We excluded stillbirths due to congenital anomalies, women with hypertensive disorders or diabetes, and plural births, to focus on fetuses and women without these known contributing conditions. We used Poisson regression to estimate relative risks (RR) and 95% confidence intervals (CI). Separate models were run for stillbirths delivered at 20-23, 24-27, 28-31, 32-36, 37-41 weeks, relative to liveborn deliveries at 37-41 weeks.

resultsFor stillbirth at 20-23 weeks, RRs were elevated for all race-ethnicity and parity groups. The RR for a 20-unit change in BMI (which reflects the approximate BMI difference between a normal weight and an Obese III woman) was 3.5 (95% CI 2.2, 5.6) for nulliparous white women and ranged from 1.8 to 5.0 for other sub-groups. At 24-27 weeks, the association was significant (p<0.05) only for multiparous non-Hispanic whites; at 28-31 weeks, for multiparous whites and nulliparous whites and blacks; at 32-36 weeks, for multiparous whites and nulliparous blacks; and at 37-41 weeks, for all groups except nulliparous blacks. The pattern of results was similar when restricted to stillbirths due to unknown causes and somewhat stronger when restricted to stillbirths attributable to obstetric causes.

conclusionIncreased risks were observed across all gestational ages, and some evidence of heterogeneity of the associations was observed by race-ethnicity and parity.

Indexed as

Pregnancy ComplicationsStillbirthAdultBlack or African AmericanBlack PeopleBody WeightCaliforniaEthnicityFemaleGestational AgeHumansMiddle AgedMothersObesityParityPoisson Distribution

Identifiers

PMID26466315
PMCPMC4605840
OpenAlexW2213978094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.