Evidence map›Paper›PMID 26466290›Full record

ArticleOptics letters2014

Sheet-scanned dual-axis confocal microscopy using Richardson-Lucy deconvolution.

D Wang, D Meza, Y Wang, L Gao, J T C Liu

Abstract readEvaluation Study
In one paragraph

Article in Optics letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Dual-axis confocal microscopy for point-of-care pathology.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

D Wang
D Meza
Y Wang
L Gao
J T C Liu

Funding

Line-scanned MEMS-based dual-axis confocal microscopy to detect oral lesions in vR01DE023497 · NIDCR · UNIVERSITY OF WASHINGTON · PI LIU, JONATHAN T.C. · 2012 to 2014
$2.4M
Intraoperative confocal microscopy for quantitative delineation of low-grade glioR01CA175391 · NCI · UNIVERSITY OF WASHINGTON · PI LIU, JONATHAN T.C., SANAI, NADER · 2014 to 2018
$1.7M
Dual-axis Confocal Microscope for Image-guided Resection of MedulloblastomaR00EB008557 · NIBIB · STATE UNIVERSITY NEW YORK STONY BROOK · PI LIU, JONATHAN T.C. · 2010 to 2012
$724k
NCI NIH HHS R01 CA175391NIBIB NIH HHS R00 EB008557NIDCR NIH HHS R01 DE023497
6 · The paper itself

Abstract

We have previously developed a line-scanned dual-axis confocal (LS-DAC) microscope with subcellular resolution suitable for high-frame-rate diagnostic imaging at shallow depths. Due to the loss of confocality along one dimension, the contrast (signal-to-background ratio) of a LS-DAC microscope is deteriorated compared to a point-scanned DAC microscope. However, by using a sCMOS camera for detection, a short oblique light-sheet is imaged at each scanned position. Therefore, by scanning the light sheet in only one dimension, a thin 3D volume is imaged. Both sequential two-dimensional deconvolution and three-dimensional deconvolution are performed on the thin image volume to improve the resolution and contrast of one en face confocal image section at the center of the volume, a technique we call sheet-scanned dual-axis confocal (SS-DAC) microscopy.

Indexed as

AlgorithmsArtifactsAnimalsEquipment DesignEquipment Failure AnalysisImage EnhancementImage Interpretation, Computer-AssistedImaging, Three-DimensionalMiceMicroscopy, ConfocalReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID26466290
PMCPMC4608245

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.