ArticlePloS one2015
The Effect of Different Types of Musculoskeletal Injuries on Blood Concentration of Serum Amyloid A in Thoroughbred Racehorses.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- How Inflamed Is the Horse in Training? Insights into Exercise-Induced Acute Phase Response in Endurance Horses.International journal of molecular sciences · 2026Review
- Effect of trauma on the concentration of selected feline acute phase proteins.Journal of feline medicine and surgery · 2026Article
- Assessing animal welfare impacts of cosmetic manipulations in dromedary camels: insights from oxidative and inflammatory biomarkers.Frontiers in veterinary science · 2026Article
- Differences in bone turnover markers and injury risks between local and international horses: A Victorian Spring Racing Carnival study.Equine veterinary journal · 2025Article
- Adrenoceptor-stimulated inflammatory response in stress-induced serum amyloid A synthesis.Psychopharmacology · 2019Article
- Serum amyloid A in equine health and disease.Equine veterinary journal · 2019Review
- Revisiting predictive biomarkers of musculoskeletal injury in thoroughbred racehorses: longitudinal study in polish population.BMC veterinary research · 2019Article
- Proteomic Markers of Non-functional Overreaching During the Race Across America (RAAM): A Case Study.Frontiers in physiology · 2019Article
- Activities of Daily Living and Determinant Factors among Older Adult Subjects with Lower Body Fracture after Discharge from Hospital: A Prospective Study.International journal of environmental research and public health · 2018Article
- Profiling of exercise-induced transcripts in the peripheral blood cells of Thoroughbred horses.Journal of equine science · 2016Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTraining-induced muscle, skeletal and joint trauma may result in acute phase response reflected by the changes in the blood concentration of serum amyloid A (SAA) in racehorses. It remains yet unclear if such systemic reaction could be triggered by sport injuries and what is the impact of different types of musculoskeletal trauma on SAA concentrations in racehorses. This study aimed to determine changes in the SAA blood concentration in racehorses with different types of injuries of musculoskeletal system. MATERIALS AND
methodsThe study involved 28 racehorses diagnosed after the race with bone fractures (n = 7), dorsal metacarpal disease (n = 11), joint trauma (n = 4) or tendon and muscle trauma (n = 6) and 28 healthy control racehorses. Serum samples were collected twice, between 1 and 4 days of the injury or succesful completion of the race. SAA concentration was measured using the commercial ELISA kit. Differences between mean SAA concentration in respective groups were analyzed using ANOVA and Tukey post-hoc test.
resultsMean SAA concentration within the first 4 days of the injury of muscle and tendon was significantly higher than in bone fractures, dorsal metacarpal disease, joint trauma or in the healthy horses (p<0,001). There were no significant differences between the other groups.
conclusionsStrain injuries of muscle and tendons can cause a moderate increase in SAA blood concentration in racehorses, reflecting the occurrence of the acute phase response. Similar reaction is not observed in the stress-related bone injuries.
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