Evidence map›Paper›PMID 26465666›Full record

SynthesisRevista de saude publica2015

Gender in the allocation of organs in kidney transplants: meta-analysis.

Erika Vieira Almeida e Santiago, Micheline Rosa Silveira, Vânia Eloisa de Araújo, Katia de Paula Farah, Francisco de Assis Acurcio, Maria das Graças Braga Ceccato

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Revista de saude publica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Impact of Size Matching Based on Donor-Recipient Height on Kidney Transplant Outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Observational
  4. Pathogens (Basel, Switzerland) · 2020
    Article
  5. Association of Sex with Risk of Kidney Graft Failure Differs by Age.Journal of the American Society of Nephrology : JASN · 2017
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erika Vieira Almeida e SantiagoFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BR.
Micheline Rosa SilveiraFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BR.
Vânia Eloisa de AraújoDepartamento de Odontologia, Instituto de Ciências Biológicas e da Saúde. Pontifícia, Universidade Católica de Minas Gerais, Belo Horizonte, MG, BR.
Katia de Paula FarahDepartamento de Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BR.
Francisco de Assis AcurcioFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BR.
Maria das Graças Braga CeccatoFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledOBJECTIVE To analyze whether gender influence survival results of kidney transplant grafts and patients.METHODS Systematic review with meta-analysis of cohort studies available on Medline (PubMed), LILACS, CENTRAL, and Embase databases, including manual searching and in the grey literature. The selection of studies and the collection of data were conducted twice by independent reviewers, and disagreements were settled by a third reviewer. Graft and patient survival rates were evaluated as effectiveness measurements. Meta-analysis was conducted with the Review Manager® 5.2 software, through the application of a random effects model. Recipient, donor, and donor-recipient gender comparisons were evaluated.

resultsTwenty-nine studies involving 765,753 patients were included. Regarding graft survival, those from male donors were observed to have longer survival rates as compared to the ones from female donors, only regarding a 10-year follow-up period. Comparison between recipient genders was not found to have significant differences on any evaluated follow-up periods. In the evaluation between donor-recipient genders, male donor-male recipient transplants were favored in a statistically significant way. No statistically significant differences were observed in regards to patient survival for gender comparisons in all follow-up periods evaluated.CONCLUSIONS The quantitative analysis of the studies suggests that donor or recipient genders, when evaluated isolatedly, do not influence patient or graft survival rates. However, the combination between donor-recipient genders may be a determining factor for graft survival.

Indexed as

Graft SurvivalSex FactorsBrazilFemaleHumansKidney TransplantationMaleTime Factors

Identifiers

PMID26465666
PMCPMC4587823

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.