Evidence map›Paper›PMID 26465120›Full record

ArticleMedical care2015

Nonelective Rehospitalizations and Postdischarge Mortality: Predictive Models Suitable for Use in Real Time.

Gabriel J Escobar, Arona Ragins, Peter Scheirer, Vincent Liu, Jay Robles, Patricia Kipnis

Abstract read
In one paragraph

Article in Medical care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gabriel J Escobar*Division of Research, Kaiser Permanente Northern California, Oakland †Department of Inpatient Pediatrics, Kaiser Permanente Medical Center, Walnut Creek ‡Decision Support, Kaiser Foundation Health Plan Inc., Oakland §Intensive Care Department, Kaiser Permanente Medical Center, Santa Clara, CA.
Arona Ragins
Peter Scheirer
Vincent Liu
Jay Robles
Patricia Kipnis

Funding

Data-driven Precision medicine in sepsisK23GM112018 · NIGMS · KAISER FOUNDATION RESEARCH INSTITUTE · PI LIU, VINCENT · 2014 to 2017
$768k
NIGMS NIH HHS K23 GM112018NIGMS NIH HHS K23GM112018
6 · The paper itself

Abstract

backgroundHospital discharge planning has been hampered by the lack of predictive models.

objectiveTo develop predictive models for nonelective rehospitalization and postdischarge mortality suitable for use in commercially available electronic medical records (EMRs).

designRetrospective cohort study using split validation.

settingIntegrated health care delivery system serving 3.9 million members.

participantsA total of 360,036 surviving adults who experienced 609,393 overnight hospitalizations at 21 hospitals between June 1, 2010 and December 31, 2013.

main outcome measureA composite outcome (nonelective rehospitalization and/or death within 7 or 30 days of discharge).

resultsNonelective rehospitalization rates at 7 and 30 days were 5.8% and 12.4%; mortality rates were 1.3% and 3.7%; and composite outcome rates were 6.3% and 14.9%, respectively. Using data from a comprehensive EMR, we developed 4 models that can generate risk estimates for risk of the combined outcome within 7 or 30 days, either at the time of admission or at 8 AM on the day of discharge. The best was the 30-day discharge day model, which had a c-statistic of 0.756 (95% confidence interval, 0.754-0.756) and a Nagelkerke pseudo-R of 0.174 (0.171-0.178) in the validation dataset. The most important predictors-a composite acute physiology score and end of life care directives-accounted for 54% of the predictive ability of the 30-day model. Incorporation of diagnoses (not reliably available for real-time use) did not improve model performance.

conclusionsIt is possible to develop robust predictive models, suitable for use in real time with commercially available EMRs, for nonelective rehospitalization and postdischarge mortality.

Indexed as

Health Status IndicatorsModels, StatisticalAdultAgedFemaleHumansMaleMiddle AgedMortalityOutcome Assessment, Health CarePatient DischargePatient ReadmissionRisk AssessmentSurvivorsUnited StatesYoung Adult

Identifiers

PMID26465120
PMCPMC4605276

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.