ArticleInternational journal of chronic diseases2014
Evaluation of the Mean Platelet Volume and Red Cell Distribution Width in FMF: Are They Related to Subclinical Inflammation or Not?
Article in International journal of chronic diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Hematological Markers as Predictors of Attack and Remission Phases in Pediatric Familial Mediterranean Fever.Journal of clinical medicine · 2026Article
- Evaluation of Hematological Parameters as Markers for Subclinical Inflammation in Adults with Familial Mediterranean Fever.Middle East journal of digestive diseases · 2024Article
- Pan-Immune-Inflammation Value Could Be a New Marker to Predict Amyloidosis and Disease Severity in Familial Mediterranean Fever.Diagnostics (Basel, Switzerland) · 2024Article
- Acute Ischemic Stroke in Tubercular Meningitis Patients Without Conventional Vascular Risk Factors: A Retrospective Case Control Study.Journal of inflammation research · 2022Article
- The role of platelet to mean platelet volume ratio in the identification of adult-onset still's disease from sepsis.Clinics (Sao Paulo, Brazil) · 2021Article
- Assessment of Mean Platelet Volume in Patients with AA Amyloidosis and AA Amyloidosis Secondary to Familial Mediterranean Fever: A Retrospective Chart - Review Study.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Evaluation of hematological parameters in children with FMF.Clinical rheumatology · 2019Article
- A Logistic Regression Model for Noninvasive Prediction of AFP-Negative Hepatocellular Carcinoma.Technology in cancer research & treatment · 2019Article
- Mean platelet volume can estimate the current vasculitis activity of microscopic polyangiitis.Rheumatology international · 2018Article
- Clinical Significance of Routine Blood Test-Associated Inflammatory Index in Breast Cancer Patients.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- Red cell distribution width is associated with albuminuria in adults with familial Mediterranean fever.The Kaohsiung journal of medical sciences · 2016Article
- The relationship between red cell distribution width and homozygous M694V mutation in familial Mediterranean fever patients.Annals of Saudi medicineArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this paper we want to demonstrate whether higher than normal levels of RDW, and lower than normal levels of MPV can be used as indicators of subclinical inflammation and tools for treatment decision in FMF or not. The participants in this study included 89 patients with FMF during attack-free periods and 30 healthy controls. The RDW and platelet counts were significantly higher, while the MPV was significantly lower in the patients with FMF group than healthy control group (P < 0.001; P = 0.005; P < 0.001, resp.). In the attack-free FMF group, a negative correlation was found between the MPV and RDW values (P < 0.001, r = -0.40). The positive correlation was found between the RDW and ESR (r = 0.23, P = 0.028). And the negative correlation was found between the MPV and CRP (r = -0.216, P = 0.042). Consequently, our results suggest that low MPV and high RDW levels may provide additional information about subclinical inflammation in FMF patients. But other strong predisposing factors affecting subclinical inflammation in FMF should be considered. Further studies with large numbers of patients are needed. Treatment of FMF should include not only prevention of acute attacks but also decreasing of the subclinical inflammation.
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Registered trials
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