ArticleJundishapur journal of microbiology2015
Detection of pap, sfa, afa, foc, and fim Adhesin-Encoding Operons in Uropathogenic Escherichia coli Isolates Collected From Patients With Urinary Tract Infection.
Article in Jundishapur journal of microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Phylogenetic Group Distribution of UropathogenicFrontiers in cellular and infection microbiology · 2022Pooled it
- Distribution of Uropathogens and Molecular Characterisation of Virulence Genes of UropathogenicPathogens (Basel, Switzerland) · 2026Article
- Selection, Comparative Genomics, and Potential Probiotic Features of Escherichia coli 5C, a pks-Negative Strain Isolated from Healthy Infant Donor Feces.Probiotics and antimicrobial proteins · 2026Article
- Current Insights into Antibiotic Resistance in UropathogenicAntibiotics (Basel, Switzerland) · 2025Review
- Five-Year Analysis of afa Gene Prevalence in Uropathogenic Escherichia coli Isolates: A Global Perspective.Journal of clinical laboratory analysis · 2025Article
- UropathogenicInternational journal of molecular sciences · 2025Article
- Multiplex PCR Amplification for the Detection of Biofilm and Extended-spectrum Beta-Lactamase Resistance Genes and Antibiotic Resistance Patterns in UropathogenicArchives of Razi Institute · 2025Article
- Distinct Escherichia coli transcriptional profiles in the guts of recurrent UTI sufferers revealed by pangenome hybrid selection.Nature communications · 2024Article
- Distribution of chaperone-usher fimbriae and curli fimbriae among uropathogenic Escherichia coli.BMC microbiology · 2024Article
- DistinctbioRxiv : the preprint server for biology · 2024Article
- Detection of phylogrouping, adhesin, and extended spectrum β-lactamases genes in hospital acquired uropathogenic Escherichia coli isolates.Molecular biology reports · 2024Article
- Diagnosis of extraintestinal pathogenicCurrent research in microbial sciences · 2024Review
- Genome characterization of a multi-drug resistantFrontiers in microbiology · 2024Article
- UropathogenicMicroorganisms · 2023Review
- Dynamic single cell analysis in a proximal-tubule-on-chip reveals heterogeneous epithelial colonization strategies of uropathogenicFEMS microbes · 2023Article
- Genetic diversity and virulence characteristics of biofilm-producing uropathogenic Escherichia coli.International microbiology : the official journal of the Spanish Society for Microbiology · 2022Article
- Phenotypic and Genotypic Properties of Fluoroquinolone-Resistant,Microorganisms · 2021Article
- A One Health Perspective for Defining and DecipheringComparative medicine · 2021Review
- Isolation, Characterization and Genomic Analysis of a Novel Bacteriophage VB_EcoS-Golestan Infecting Multidrug-Resistant Escherichia coli Isolated from Urinary Tract Infection.Scientific reports · 2020Article
- Distribution of virulence genes and phylogenetics of uropathogenic Escherichia coli among urinary tract infection patients in Addis Ababa, Ethiopia.BMC infectious diseases · 2020Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUropathogenic Escherichia coli (UPEC) with its virulence factors is the most prevalent cause of urinary tract infection (UTI).
objectivesThis study aimed to determine the occurrence of fim, pap, sfa, and afa genes among 100 UPEC isolates collected from patients diagnosed with UTI. MATERIALS AND
methodsA total of 100 UPEC isolates were obtained from urine samples of patients with UTI. The prevalence of 5 virulence genes encoding type 1 fimbriae (fimH), pili associated with pyelonephritis (pap), S and F1C fimbriae (sfa and foc) and afimbrial adhesins (afa) were determined through PCR method. We also investigated the phylogenetic background of all isolates. In addition, the distribution of adhesin-encoding operons between the phylogroups was assessed.
resultsThe prevalence of genes encoding for fimbrial adhesive systems was 95% for fim, 57% for pap, 16% for foc, and 81% for sfa. The operons encoding for afa afimbrial adhesins were identified in 12% of isolates. The various combinations of detected genes were designated as virulence patterns. The fim gene, which occurred in strains from all phylogenetic groups (A, B1, B2, and D) was evaluated and no significant differences were found among these groups. Conversely, significant differences were observed in relation to pap, afa, foc, and sfa operons.
conclusionsThese results indicate that the PCR method is a powerful genotypic assay for the detection of adhesin-encoding operons. Thus, this assay can be recommended for clinical use to detect virulent urinary E. coli strains, as well as epidemiological studies.
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