Evidence map›Paper›PMID 26464355›Full record

ArticlePhysics in medicine and biology2015

Computer-aided detection system for clustered microcalcifications in digital breast tomosynthesis using joint information from volumetric and planar projection images.

Ravi K Samala, Heang-Ping Chan, Yao Lu, Lubomir M Hadjiiski, Jun Wei, Mark A Helvie

Open access · greenAbstract read
In one paragraph

Article in Physics in medicine and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ravi K SamalaDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109842, USA.
Heang-Ping ChanDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109842, USA.
Yao LuDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109842, USA.
Lubomir M HadjiiskiDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109842, USA.
Jun WeiDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109842, USA.
Mark A HelvieDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109842, USA.
University of Michigan–Ann Arbor · US

Funding

Combined Digital X-Ray, Optical, and Ultrasound Breast ImagingR01CA091713 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARSON, PAUL L · 2002 to 2012
$10.1M
Improvement of microcalcification detection in digital breast tomosynthesisR01CA151443 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHAN, HEANG-PING · 2011 to 2015
$3.0M
NCI NIH HHS R01 CA091713NCI NIH HHS R01 CA151443NCI NIH HHS R01CA91713
6 · The paper itself

Abstract

We propose a novel approach for the detection of microcalcification clusters (MCs) using joint information from digital breast tomosynthesis (DBT) volume and planar projection (PPJ) image. A data set of 307 DBT views was collected with IRB approval using a prototype DBT system. The system acquires 21 projection views (PVs) from a wide tomographic angle of 60° (60°-21PV) at about twice the dose of a digital mammography (DM) system, which allows us the flexibility of simulating other DBT acquisition geometries using a subset of the PVs. In this study, we simulated a 30° DBT geometry using the central 11 PVs (30°-11PV). The narrower tomographic angle is closer to DBT geometries commercially available or under development and the dose is matched approximately to that of a DM. We developed a new joint-CAD system for detection of clustered microcalcifications. The DBT volume was reconstructed with a multiscale bilateral filtering regularized method and a PPJ image was generated from the reconstructed volume. Task-specific detection strategies were designed to combine information from the DBT volume and the PPJ image. The data set was divided into a training set (127 views with MCs) and an independent test set (104 views with MCs and 76 views without MCs). The joint-CAD system outperformed the individual CAD systems for DBT volume or PPJ image alone; the differences in the test performances were statistically significant (p  <  0.05) using JAFROC analysis.

Indexed as

CalcinosisCone-Beam Computed TomographyHumansMammographyRadiographic Image Enhancement

Identifiers

PMID26464355
PMCPMC4733604
OpenAlexW2280541663

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.