ArticleJournal of materials science. Materials in medicine2015
On the influence of various physicochemical properties of the CNTs based implantable devices on the fibroblasts' reaction in vitro.
Article in Journal of materials science. Materials in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Synergistic Electronic Modulation in Nitrogen, Sulfur, and Boron-Doped Graphene Nanoribbons for Enhanced Oxygen Reduction Electrocatalysis.ACS omega · 2026Article
- A Prospective and Cost-Effective Voltammetric-Chemometric Approach for the Discrimination and Quantification of Melamine and Urea in Milk.ACS omega · 2026Article
- Energies Exploration for the Troponine Molecule Supported on Carbon Nanomaterials: DFT Study.ACS omega · 2023Article
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Authors and funding
6 authors.
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Abstract
Coating the material with a layer of carbon nanotubes (CNTs) has been a subject of particular interest for the development of new biomaterials. Such coatings, made of properly selected CNTs, may constitute an implantable electronic device that facilitates tissue regeneration both by specific surface properties and an ability to electrically stimulate the cells. The goal of the presented study was to produce, evaluate physicochemical properties and test the applicability of highly conductible material designed as an implantable electronic device. Two types of CNTs with varying level of oxidation were chosen. The process of coating involved suspension of the material of choice in the diluent followed by the electrophoretic deposition to fabricate layers on the surface of a highly biocompatible metal-titanium. Presented study includes an assessment of the physicochemical properties of the material's surface along with an electrochemical evaluation and in vitro biocompatibility, cytotoxicity and apoptosis studies in contact with the murine fibroblasts (L929) in attempt to answer the question how the chemical composition and CNTs distribution in the layer alters the electrical properties of the sample and whether any of these properties have influenced the overall biocompatibility and stimulated adhesion of fibroblasts. The results indicate that higher level of oxidation of CNTs yielded materials more conductive than the metal they are deposited on. In vitro study revealed that both materials were biocompatible and that the cells were not affected by the amount of the functional group and the morphology of the surface they adhered to.
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