Evidence map›Paper›PMID 26464011›Full record

ArticleThe Journal of antibiotics2016

Aspergillus mulundensis sp. nov., a new species for the fungus producing the antifungal echinocandin lipopeptides, mulundocandins.

Gerald F Bills, Qun Yue, Li Chen, Yan Li, Zhiqiang An, Jens C Frisvad

Abstract read
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In one paragraph

Article in The Journal of antibiotics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Classification ofStudies in mycology · 2020
    Article
  6. Article
  7. Effect of SDS on release of intracellular pneumocandin BApplied microbiology and biotechnology · 2019
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Studies in mycology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gerald F BillsTexas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Centre at Houston, Houston, TX, USA.
Qun YueTexas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Centre at Houston, Houston, TX, USA.
Li ChenTexas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Centre at Houston, Houston, TX, USA.
Yan LiTexas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Centre at Houston, Houston, TX, USA.
Zhiqiang AnTexas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Centre at Houston, Houston, TX, USA.
Jens C FrisvadCenter for Microbial Biotechnology, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The invalidly published name Aspergillus sydowii var. mulundensis was proposed for a strain of Aspergillus that produced new echinocandin metabolites designated as the mulundocadins. Reinvestigation of this strain (Y-30462=DSMZ 5745) using phylogenetic, morphological, and metabolic data indicated that it is a distinct and novel species of Aspergillus sect. Nidulantes. The taxonomic novelty, Aspergillus mulundensis, is introduced for this historically important echinocandin-producing strain. The closely related A. nidulans FGSC A4 has one of the most extensively characterized secondary metabolomes of any filamentous fungus. Comparison of the full-genome sequences of DSMZ 5745 and FGSC A4 indicated that the two strains share 33 secondary metabolite biosynthetic gene clusters. These shared gene clusters represent ~45% of the total secondary metabolome of each strain, thus indicating a high level intraspecific divergence in terms of secondary metabolism.

Indexed as

PhylogenyAntifungal AgentsAspergillusDNA, FungalEchinocandinsLipopeptidesMetabolomeMultigene FamilySecondary MetabolismSequence Analysis, DNASpecies SpecificityAntifungal AgentsDNA, FungalEchinocandinsLipopeptidesmulundocandin

Identifiers

PMID26464011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.