ArticleBirth (Berkeley, Calif.)2015
The Association Between Common Labor Drugs and Suckling When Skin-to-Skin During the First Hour After Birth.
Article in Birth (Berkeley, Calif.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Maternal and newborn plasma oxytocin levels in response to maternal synthetic oxytocin administration during labour, birth and postpartum - a systematic review with implications for the function of the oxytocinergic system.BMC pregnancy and childbirth · 2023Pooled it
- Parenteral opioids for maternal pain management in labour.The Cochrane database of systematic reviews · 2018Pooled it
- The effect of intravenous hyoscine butylbromide on slow progress in labor (BUSCLAB): A double-blind randomized placebo-controlled trial.PLoS medicine · 2024Trial
- Association of Self-Reported Physical Fitness during Late Pregnancy with Birth Outcomes and Oxytocin Administration during Labour-The GESTAFIT Project.International journal of environmental research and public health · 2021Trial
- Effects of Adrenaline on maternal and fetal fentanyl absorption in epidural analgesia: A randomized trial.Acta anaesthesiologica Scandinavica · 2018Trial
- De-medicalization of birth by reducing the use of oxytocin for augmentation among first-time mothers - a prospective intervention study.BMC pregnancy and childbirth · 2018Trial
- Induction of labor is not associated with decreased rates of breastfeeding in late preterm pregnancies.AJOG global reports · 2026Article
- Diagnosing Breastfeeding Difficulties: Where Do We Stand?Maternal & child nutrition · 2026Review
- The impact of mother-infant rooming-in and continuous skin-to-skin contact on newborns.Frontiers in pediatrics · 2025Article
- The impact of implementing and sustaining the international guidelines for skin-to-skin contact in the first hour after birth in Uganda.Scientific reports · 2024Article
- Association between combined use of epidural analgesia and oxytocin administration during labor and offspring outcomes: a narrative review and proposal.Nagoya journal of medical science · 2024Review
- Impact of intrapartum oxytocin administration on neonatal sucking behavior and breastfeeding.Scientific reports · 2024Article
- Endorphins, Sexuality, and Reproduction.Advances in neurobiology · 2024Article
- A longitudinal study of the association of epidural anesthesia and low-dose synthetic oxytocin regimens with breast milk supply and breastfeeding rates.Scientific reports · 2023Article
- A prolonged latent phase: An early career in oxytocin during birth.Comprehensive psychoneuroendocrinology · 2023Article
- Article
- Effect of neonatal breast crawl on breastfeeding: a prospective cohort study.Frontiers in pediatrics · 2023Article
- Article
- Epidural AnalgesiaFrontiers in neuroscience · 2021Article
- Birth signalling hormones and the developmental consequences of caesarean delivery.Journal of neuroendocrinology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntrapartum drugs, including fentanyl administered via epidural and synthetic oxytocin, have been previously studied in relation to neonatal outcomes, especially breastfeeding, with conflicting results. We examined the normal neonatal behavior of suckling within the first hour after a vaginal birth while in skin-to-skin contact with mother in relation to these commonly used drugs. Suckling in the first hour after birth has been shown in other studies to increase desirable breastfeeding outcomes.
methodProspective comparative design. Sixty-three low-risk mothers self-selected to labor with intrapartum analgesia/anesthesia or not. Video recordings of infants during the first hour after birth while being held skin-to-skin with their mother were coded and analyzed to ascertain whether or not they achieved Stage 8 (suckling) of Widström's 9 Stages of newborn behavior during the first hour after birth.
resultsA strong inverse correlation was found between the amount and duration of exposure to epidural fentanyl and the amount of synthetic oxytocin against the likelihood of achieving suckling during the first hour after a vaginal birth.
conclusionsResults suggest that intrapartum exposure to the drugs fentanyl and synthetic oxytocin significantly decreased the likelihood of the baby suckling while skin-to-skin with its mother during the first hour after birth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.