ArticleInsects2015
Parasitic Manipulation of Host Behaviour: Baculovirus SeMNPV EGT Facilitates Tree-Top Disease in Spodoptera exigua Larvae by Extending the Time to Death.
Article in Insects, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- BV/ODV-E26 is a conserved baculoviral inhibitory factor for optimizing viral virulence in lepidopteran hosts.iScience · 2025Article
- Insect circadian plasticity as a proposed target for the expression of parasite extended phenotypes.Npj biological timing and sleep · 2025Review
- Viral- and fungal-mediated behavioral manipulation of hosts: summit disease.Applied microbiology and biotechnology · 2024Review
- Article
- Small Talk: On the Possible Role of Trans-Kingdom Small RNAs during Plant-Virus-Vector Tritrophic Communication.Plants (Basel, Switzerland) · 2023Review
- The PI3K/AKT Pathway andGenes · 2022Article
- Viruses of the Fall ArmywormViruses · 2021Review
- Insect Behavioral Change and the Potential Contributions of Neuroinflammation-A Call for Future Research.Genes · 2021Review
- High-resolution analysis of baculovirus-induced host manipulation in the domestic silkworm,Parasitology · 2021Article
- Genetic Underpinnings of Host Manipulation byG3 (Bethesda, Md.) · 2020Article
- Zombie ant death grip due to hypercontracted mandibular muscles.The Journal of experimental biology · 2019Article
- Cross-talking between baculoviruses and host insects towards a successful infection.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Effect of Different Light Spectrum inInsects · 2018Article
- Baculovirus PTP2 Functions as a Pro-Apoptotic Protein.Viruses · 2018Article
- Baculovirus infection triggers a positive phototactic response in caterpillars: a response to Dobson et al. (2015).Biology letters · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many parasites enhance their dispersal and transmission by manipulating host behaviour. One intriguing example concerns baculoviruses that induce hyperactivity and tree-top disease (i.e., climbing to elevated positions prior to death) in their caterpillar hosts. Little is known about the underlying mechanisms of such parasite-induced behavioural changes. Here, we studied the role of the ecdysteroid UDP-glucosyltransferase (egt) gene of Spodoptera exigua multiple nucleopolyhedrovirus (SeMNPV) in tree-top disease in S. exigua larvae. Larvae infected with a mutant virus lacking the egt gene exhibited a shorter time to death and died before the induction of tree-top disease. Moreover, deletion of either the open reading frame or the ATG start codon of the egt gene prevented tree-top disease, indicating that the EGT protein is involved in this process. We hypothesize that SeMNPV EGT facilitates tree-top disease in S. exigua larvae by prolonging the larval time to death. Additionally, we discuss the role of egt in baculovirus-induced tree-top disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.