Evidence map›Paper›PMID 26462986›Full record

ArticleThe Journal of antimicrobial chemotherapy2016

PBP2a substitutions linked to ceftaroline resistance in MRSA isolates from the UK.

Ewan M Harrison, Xiaoliang Ba, Beth Blane, Matthew J Ellington, Anette Loeffler, Robert L R Hill, Mark A Holmes, Sharon J Peacock

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of antimicrobial chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Evaluation ofIranian journal of microbiology · 2021
    Article
  3. Antimicrobial resistance in methicillin-resistantAntimicrobial agents and chemotherapy · 2019
    Review
  4. Antibiotic Resistance and the MRSA Problem.Microbiology spectrum · 2019
    Review
  5. Article
  6. Antimicrobial activity of ceftaroline against methicillin-resistant Staphylococcus aureus (MRSA) isolates collected in 2013-2014 at the Geneva University Hospitals.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Article
  7. Upregulated effects of miR-7 in methicillin-resistantExperimental and therapeutic medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ewan M HarrisonDepartment of Medicine, University of Cambridge, Cambridge, UK eh439@cam.ac.uk.
Xiaoliang BaDepartment of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Beth BlaneDepartment of Medicine, University of Cambridge, Cambridge, UK.
Matthew J EllingtonClinical Microbiology and Public Health Laboratory, Public Health England, Cambridge, UK.
Anette LoefflerRoyal Veterinary College, Hawkshead Campus, University of London, London, UK.
Robert L R HillAntimicrobial Resistance and Healthcare Associated Infections Reference Unit, Public Health England, London, UK.
Mark A HolmesDepartment of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Sharon J PeacockDepartment of Medicine, University of Cambridge, Cambridge, UK Clinical Microbiology and Public Health Laboratory, Public Health England, Cambridge, UK Wellcome Trust Sanger Institute, Hinxton, UK.

Funding

Medical Research Council G1000803Medical Research Council G1001787Medical Research Council G1001787/1Medical Research Council MR/P007201/1Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

beta-Lactam ResistanceAmino Acid SubstitutionAnimalsAnti-Bacterial AgentsBacterial ProteinsCeftarolineCephalosporinsHumansMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsPenicillin-Binding ProteinsStaphylococcal InfectionsUnited KingdomAnti-Bacterial AgentsBacterial ProteinsCeftarolineCephalosporinsmecA protein, Staphylococcus aureusPenicillin-Binding Proteins

Identifiers

PMID26462986
PMCPMC4681373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.