Evidence map›Paper›PMID 26462561›Full record

ReviewJournal of hematology & oncology2015

The roles of stem cell memory T cells in hematological malignancies.

Ling Xu, Yikai Zhang, Gengxin Luo, Yangqiu Li

Abstract readReview
In one paragraph

Review in Journal of hematology & oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
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  3. Review
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  5. Antigen-presenting B cells promote TCF-1Frontiers in immunology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ling XuDepartment of Hematology, First Affiliated Hospital, Jinan University, Guangzhou, 510632, China. lingxu114@163.com.
Yikai ZhangDepartment of Hematology, First Affiliated Hospital, Jinan University, Guangzhou, 510632, China. jnuyikai@163.com.
Gengxin LuoDepartment of Hematology, First Affiliated Hospital, Jinan University, Guangzhou, 510632, China. jdluogx@163.com.
Yangqiu LiDepartment of Hematology, First Affiliated Hospital, Jinan University, Guangzhou, 510632, China. yangqiuli@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adoptive cell therapy (ACT) is rapidly migrating from bench to clinical therapy for hematological malignancies. Recently, a new subtype of memory T cells, stem cell memory T (TSCM) cells, was shown to be one of the most favorable subsets for ACT. TSCM has high self-renewal capacity and is associated with superior T cell engraftment, persistence, and antitumor immunity. In this review, we focused on the characteristics of antigen-specific TSCM cells and discussed their potential for immunotherapy targeting hematological malignancies.

Indexed as

Cell DifferentiationHematologic NeoplasmsHematopoietic Stem Cell TransplantationHumansImmunologic MemoryImmunophenotypingImmunotherapy, AdoptiveModels, ImmunologicalT-Lymphocyte Subsets

Identifiers

PMID26462561
PMCPMC4605076

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.