Evidence map›Paper›PMID 26462290›Full record

ArticleClinical epidemiology and global health2015

Community mass treatment with azithromycin for trachoma: Factors associated with change in participation of children from the first to the second round.

Elizabeth N Ssemanda, Harran Mkocha, Joshua Levens, Beatriz Munoz, Sheila K West

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Article in Clinical epidemiology and global health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Elizabeth N SsemandaDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.
Harran MkochaKongwa Trachoma Project, Kongwa, Tanzania.
Joshua LevensDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.
Beatriz MunozDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.
Sheila K WestDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.

Funding

Wilmer Core Grant for Vision ResearchP30EY001765 · NEI · JOHNS HOPKINS UNIVERSITY · PI Jiang Qian · 1985 to 2026
$22.1M
CLINICAL TRIALS TRAINING PROGRAM IN VISION RESEARCHT32EY007127 · NEI · JOHNS HOPKINS UNIVERSITY · PI MEINERT, CURTIS L · 1991 to 2010
$4.7M
NEI NIH HHS P30 EY001765NEI NIH HHS T32 EY007127
6 · The paper itself

Abstract

backgroundMass drug administration (MDA) with azithromycin is an important part of trachoma control programs. Maintaining high participation among children is challenging.

aimWe assessed factors identifying households with a child who changed participation from the first MDA to the second MDA compared to households where all children participated at both MDAs.

methodsTwo case-control comparisons were conducted in 11 Tanzanian communities, which underwent MDA in 2008 and 2009. The first case group (n=165) was a random sample of households with a child who changed from a 2008 non-participant to a 2009 participant (delayed participant). The second case group (n=165) was a random sample of households with a child who went from a 2008 participant to a 2009 non-participant (change to non-participant). Controls (n=330) were a random sample of households where all children participated in both rounds. Risk factors were assessed using questionnaires asked of children's guardians. Logistic models with a random-intercept were used to estimate odds ratios and 95% confidence intervals.

resultsHouseholds with delayed participation were more likely to be in communities with fewer treatment days (OR=2.98, 95% CI=1.80-4.92) and assigned to Community Treatment Assistants (CTA) with a wide area to cover (OR=1.88, 95% CI=1.09-3.23). Households with change to non-participation were more likely to live further from the distribution site (OR=3.17, 95% CI=1.19-8.46), have the guardian born outside the village with short-term residency (OR=2.64, 95% CI=1.32-5.31), and be assigned to a male CTA (OR=1.75, 95% CI=1.08-2.83).

conclusionsFactors related to program accessibility were associated with delayed participation and maintaining participation.

Indexed as

azithromycinmass drug administrationTrachoma

Identifiers

PMID26462290
PMCPMC4599782

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