Evidence map›Paper›PMID 26462233›Full record

ReviewBioinformatics and biology insights2015

Genetics of Prion Disease in Cattle.

Brenda M Murdoch, Gordon K Murdoch

Open access · goldAbstract readReview
In one paragraph

Review in Bioinformatics and biology insights, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. No association of prion protein gene (Molecular & cellular toxicology · 2022
    Article
  5. Article
  6. The First Report of Genetic Polymorphisms of the EquineAnimals : an open access journal from MDPI · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Novel Polymorphisms and Genetic Characteristics of the Prion Protein Gene (International journal of molecular sciences · 2020
    Article
  11. Article
  12. Article
  13. Bovine spongiform encephalopathy (BSE) cases born after the total feed ban.EFSA journal. European Food Safety Authority · 2017
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Brenda M MurdochAnimal and Veterinary Science, University of Idaho, Moscow, ID, USA.
Gordon K MurdochAnimal and Veterinary Science, University of Idaho, Moscow, ID, USA.
University of Idaho · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine spongiform encephalopathy (BSE) is a prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk. As a transmissible disease of livestock, it has impacted food safety, production practices, global trade, and profitability. Genetic polymorphisms that alter the prion protein in humans and sheep are associated with transmissible spongiform encephalopathy susceptibility or resistance. In contrast, there is no strong evidence that nonsynonymous mutations in the bovine prion gene (PRNP) are associated with classical BSE (C-BSE) disease susceptibility, though two bovine PRNP insertion/deletion polymorphisms, in the putative region, are associated with susceptibility to C-BSE. However, these associations do not explain the full extent of BSE susceptibility, and loci outside of PRNP appear to be associated with disease incidence in some cattle populations. This article provides a review of the current state of genetic knowledge regarding prion diseases in cattle.

Indexed as

BSEcattleprionPRNP

Identifiers

PMID26462233
PMCPMC4589088
OpenAlexW2118538978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.