ReviewCurrent opinion in microbiology2016
Dining in: intracellular bacterial pathogen interplay with autophagy.
Review in Current opinion in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Avian pathogenic Escherichia coli virulence protein Hcp2a induces incomplete autophagy in chicken HD11 cells.Poultry science · 2026Article
- Autophagy in the Lifetime of Plants: From Seed to Seed.International journal of molecular sciences · 2022Review
- Article
- Megaviruses contain various genes encoding for eukaryotic vesicle trafficking factors.Traffic (Copenhagen, Denmark) · 2022Article
- Autophagy Regulates Whitefly-Symbiont Metabolic Interactions.Applied and environmental microbiology · 2022Article
- Identification and characterization of novel infection associated transcripts in macrophages.RNA biology · 2021Article
- Ginsenoside 20(S)-Rh2 promotes cellular pharmacokinetics and intracellular antibacterial activity of levofloxacin against Staphylococcus aureus through drug efflux inhibition and subcellular stabilization.Acta pharmacologica Sinica · 2021Article
- Review
- Coxiella burnetii: international pathogen of mystery.Microbes and infection · 2020Review
- MicroRNA-106a Inhibits Autophagy Process and Antimicrobial Responses by Targeting ULK1, ATG7, and ATG16L1 During Mycobacterial Infection.Frontiers in immunology · 2020Article
- Bacterial interaction with host autophagy.Virulence · 2019Review
- Characterization of Early Stages of Human Alveolar Infection by the Q Fever AgentInfection and immunity · 2019Article
- Article
- Selective Autophagy and Xenophagy in Infection and Disease.Frontiers in cell and developmental biology · 2018Review
- Relative transcription of autophagy-related genes in Amblyomma sculptum and Rhipicephalus microplus ticks.Experimental & applied acarology · 2017Article
- Review
- Absence of Specific Chlamydia trachomatis Inclusion Membrane Proteins Triggers Premature Inclusion Membrane Lysis and Host Cell Death.Cell reports · 2017Article
- Chrysin Protects Rat Kidney from Paracetamol-Induced Oxidative Stress, Inflammation, Apoptosis, and Autophagy: A Multi-Biomarker Approach.Scientia pharmaceutica · 2017Article
- Mechanisms of action of Coxiella burnetii effectors inferred from host-pathogen protein interactions.PloS one · 2017Article
- Macrophage Autophagy and Bacterial Infections.Frontiers in immunology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Intracellular bacterial pathogens have evolved many ways to manipulate host cells for successful infection. Many of these pathogens use specialized secretion systems to inject bacterial proteins into the host cytosol that manipulate cellular processes to favor infection. Autophagy is a eukaryotic cellular remodeling process with a critical role in many diseases, including bacterial clearance. A growing field of research highlights mechanisms used by intracellular bacteria to manipulate autophagy as a pro-survival strategy. This review focuses on a select group of bacterial pathogens with diverse intracellular lifestyles that exploit autophagy-derived nutrients and membrane for survival. This group of pathogens uses secretion systems and specific effectors to subvert distinct components of autophagy. By understanding how intracellular pathogens manipulate autophagy, we gain insight not only into bacterial pathogenesis but also host cell signaling and autophagolysosome maturation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.